Definition/General
Clinical Features
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Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
[specimen type], measuring [size] cm in greatest dimension
Diagnosis
Schwannoma
Location
Location: [anatomical site in colorectum]
Histological Features
Shows spindle cells in fascicular arrangement with Antoni A and B areas. Verocay bodies present. Nuclear palisading noted.
Size and Extent
Size: [X] cm, well-circumscribed and encapsulated
Cellular Features
Spindle cells with wavy nuclei and eosinophilic cytoplasm. Mitotic activity: [X] per 10 HPF
Immunohistochemistry
S-100 protein: Positive (strong, diffuse)
CD117: Negative
Smooth muscle actin: Negative
SOX-10: Positive (nuclear)
Margins
Margins: [involved/uninvolved] (if resection specimen)
Final Diagnosis
Colorectal Schwannoma - Benign nerve sheath tumor