Overview

Definition:
-Anterior Cruciate Ligament (ACL) injuries in adolescents are particularly complex due to the presence of open physes (growth plates), which are crucial for bone growth
-Physeal-sparing techniques aim to reconstruct the ACL while minimizing disruption to these growth plates, thereby reducing the risk of premature physeal closure and subsequent limb length discrepancy or angular deformities.
Epidemiology:
-ACL injuries are increasingly common in adolescent athletes, with a rising incidence in pediatric populations
-While overall ACL injury rates are lower in younger children compared to adults, the proportion of growth plate fractures associated with ACL injuries can be higher in skeletally immature individuals
-These injuries occur most frequently during high-impact sports involving pivoting, cutting, and sudden deceleration.
Clinical Significance:
-Improper management of ACL injuries in adolescents can lead to significant long-term morbidity
-Premature physeal closure can result in limb length inequality and angular deformities (e.g., genu valgum or varum), necessitating further corrective surgeries
-Physeal-sparing techniques are therefore paramount to preserve growth potential while restoring knee stability and function, allowing adolescents to return to their desired activity levels.

Clinical Presentation

Symptoms:
-A distinct "pop" sensation at the time of injury
-Immediate onset of severe knee pain
-Significant hemarthrosis (swelling) within hours
-Inability to bear weight on the affected limb
-Feeling of instability or giving way in the knee
-Stiffness and limited range of motion.
Signs:
-Gross joint effusion
-Tenderness along the joint line and to palpation of collateral ligaments
-Positive Lachman test indicating ACL laxity
-Positive anterior drawer test
-Positive pivot shift test indicating rotational instability
-Palpable or visible deformity may be present in cases of associated fractures.
Diagnostic Criteria:
-Diagnosis is primarily clinical, supported by imaging
-Clinical diagnosis relies on a consistent history and positive findings on physical examination, particularly the Lachman test and anterior drawer test
-Radiographic evidence of associated physeal fractures (avulsion fractures, especially of the tibial spine) is critical to assess skeletal maturity and guide management
-MRI can confirm the ACL tear and evaluate associated intra-articular pathology.

Diagnostic Approach

History Taking:
-Detailed mechanism of injury is crucial (non-contact pivoting, landing from a jump)
-Ask about any previous knee injuries or pain
-Assess the adolescent's level of activity and sport participation
-Inquire about any reports of a "pop" at the time of injury
-Document presence and progression of pain and swelling
-Assess functional limitations like difficulty with stairs or walking.
Physical Examination:
-Begin with inspection for swelling, ecchymosis, and deformity
-Palpate for tenderness over the joint line, collateral ligaments, and tibial eminences
-Perform a systematic assessment of knee range of motion (active and passive)
-Evaluate ligamentous stability using Lachman, anterior drawer, posterior drawer, varus stress, and valgus stress tests
-Assess for the pivot shift phenomenon
-Assess neurovascular status distally.
Investigations:
-Plain radiographs (AP, lateral, notch views) are essential to assess skeletal maturity (Risser sign, Salter-Harris classification) and identify associated avulsion fractures, particularly tibial spine avulsions
-MRI of the knee is highly sensitive and specific for confirming the ACL tear, assessing its severity, and identifying associated injuries such as meniscal tears, collateral ligament injuries, and bone bruises
-Ultrasound may be used for effusion assessment but is not primary for ACL diagnosis.
Differential Diagnosis:
-Tibial spine avulsion fracture (often mimics ACL tear in children, but is a bony avulsion)
-Meniscal tears
-Collateral ligament injuries
-Patellar dislocation
-Osteochondral fractures
-Referred pain from hip or other sources
-Other causes of hemarthrosis in children (e.g., bleeding disorders, although rare in trauma context).

Management

Initial Management:
-RICE protocol (Rest, Ice, Compression, Elevation) to control pain and swelling
-Crutch ambulation with non-weight bearing or partial weight bearing
-Analgesia with NSAIDs or acetaminophen
-Referral to pediatric orthopedics for definitive management planning.
Surgical Management:
-The choice of surgical technique depends on the adolescent's skeletal maturity, the presence of associated injuries, and the degree of instability
-Physeal-sparing techniques are preferred to avoid growth plate injury
-These include: Transphyseal (traditional) ACL reconstruction (less preferred due to growth plate risk)
-Physeal-sparing techniques using all-epiphyseal tunnels or suspensory fixation devices that bypass or minimize disruption of the physis
-Spica casting for tibial spine avulsions in very young children
-Arthroscopic techniques often used to minimize soft tissue disruption.
Supportive Care:
-Postoperative management includes pain control, wound care, and progressive rehabilitation
-Physical therapy is critical for regaining range of motion, strength, proprioception, and neuromuscular control
-Gradual return to sports is guided by functional milestones and physician assessment
-Emotional support for the adolescent athlete and their family is also important.
Age Specific Dosing:
-Pain management in pediatric patients requires age and weight-appropriate dosing
-Acetaminophen: 10-15 mg/kg/dose PO q4-6h prn
-Ibuprofen: 5-10 mg/kg/dose PO q6-8h prn
-Opioids (e.g., Tramadol, Morphine) may be used judiciously for severe acute pain, with careful monitoring for respiratory depression
-Doses must be calculated based on current weight and renal function.

Complications

Early Complications:
-Infection (superficial or deep)
-Hemarthrosis and persistent effusion
-Stiffness and limited range of motion
-Neurovascular injury (rare)
-Gout or pseudogout flares (rare).
Late Complications:
-Premature physeal closure leading to limb length discrepancy or angular deformity (valgus/varus)
-Persistent knee instability
-Osteoarthritis
-Hardware-related issues (irritation, loosening)
-Graft failure or rerupture
-Stiffness and arthrofibrosis
-Chronic pain.
Prevention Strategies:
-Meticulous surgical technique to avoid unnecessary physeal trauma
-Appropriate graft selection and fixation
-Aggressive postoperative rehabilitation to prevent stiffness
-Patient and family education on activity modification and return-to-sport criteria
-Regular follow-up to monitor for growth disturbances and long-term outcomes.

Prognosis

Factors Affecting Prognosis:
-Skeletal maturity at time of injury and surgery
-Adherence to rehabilitation protocols
-Presence and management of associated injuries
-Quality of surgical reconstruction
-Return-to-sport decisions
-Patient's motivation and expectations.
Outcomes:
-With appropriate physeal-sparing techniques and comprehensive rehabilitation, many adolescents can achieve good functional outcomes, return to high levels of sport, and have a reduced risk of long-term complications
-However, the risk of developing osteoarthritis later in life remains higher compared to uninjured individuals
-Physeal arrest complications can significantly impact long-term limb alignment and length.
Follow Up:
-Regular clinical and radiographic follow-up is essential, particularly during periods of rapid skeletal growth
-Monitoring for signs of premature physeal closure, limb length discrepancy, or angular deformities is crucial
-Long-term follow-up (10+ years) may be warranted to assess for the development of osteoarthritis and functional status.

Key Points

Exam Focus:
-Differentiate ACL tears from tibial spine avulsions in children
-Recognize the importance of skeletal maturity (e.g., Risser sign) in surgical planning
-Understand the principles of physeal-sparing techniques vs
-transphyseal techniques
-Identify common complications like physeal arrest
-Recall RICE protocol and initial management steps.
Clinical Pearls:
-Always obtain weight-bearing AP/lateral and notch views of the knee in adolescents with suspected ACL injury
-Consider physeal injury even with a seemingly "soft tissue" mechanism
-Use arthroscopy to assess intra-articular pathology and guide surgical approach
-Early aggressive physical therapy is key to restoring function and preventing stiffness.
Common Mistakes:
-Performing transphyseal reconstruction without considering the risks of growth plate injury
-Inadequate assessment of skeletal maturity
-Delaying surgical intervention for unstable injuries
-Insufficient or inappropriate postoperative rehabilitation
-Premature return to sport without adequate recovery and strength
-Failing to adequately address associated meniscal or collateral ligament injuries.