Overview

Definition:
-Adenoid hypertrophy refers to the enlargement of the adenoid tonsil, a lymphoid tissue located in the nasopharynx
-This enlargement can obstruct the nasal airway, leading to symptoms of nasal obstruction and contributing to sleep-disordered breathing (SDB) in children.
Epidemiology:
-Adenoid hypertrophy is a common condition in children, with peak prevalence observed between the ages of 3 and 7 years
-It is a leading cause of chronic nasal obstruction and SDB in this age group
-Recurrence is possible, especially in children with a history of recurrent upper respiratory infections.
Clinical Significance:
-Untreated adenoid hypertrophy can significantly impact a child's quality of life, affecting sleep, breathing, oral feeding, speech development, and even facial growth
-Its association with SDB raises concerns about potential long-term consequences on cardiovascular health and neurocognitive development, making timely diagnosis and management crucial for pediatric residents preparing for DNB and NEET SS examinations.

Clinical Presentation

Symptoms:
-Chronic nasal obstruction, often worse at night
-Mouth breathing, leading to a characteristic "adenoid facies" with an open mouth, elongated face, and dental malocclusion
-Snoring
-Episodes of apnea or pauses in breathing during sleep
-Restless sleep
-Daytime fatigue or somnolence
-Recurrent sinopulmonary infections
-Nasal discharge (rhinorrhea)
-Difficulty feeding in infants.
Signs:
-Visible mouth breathing
-Nasal airflow limitation on examination
-Postnasal drip
-Cobblestoning of the posterior pharyngeal wall
-Enlarged tonsils (though not always proportional to adenoid size)
-Signs of otitis media with effusion (OME)
-Characteristic facial features (adenoid facies) if chronic
-In severe cases, paradoxical chest wall retractions during inspiration may be noted during sleep.
Diagnostic Criteria:
-There are no universally established diagnostic criteria for adenoid hypertrophy itself, as it is a histological finding and an anatomical consequence
-Diagnosis is primarily clinical, supported by imaging
-Sleep-disordered breathing is often diagnosed using polysomnography (PSG) to assess the severity and type of respiratory disturbance.

Diagnostic Approach

History Taking:
-Detailed history of nasal breathing difficulties, mouth breathing, snoring, witnessed apneas, sleep disturbances, and daytime symptoms
-Inquire about frequency and severity of sinopulmonary infections
-Assess feeding patterns in infants
-Family history of sleep disorders or obstructive sleep apnea
-Red flags include cyanosis, significant desaturations during sleep, failure to thrive, and severe daytime somnolence.
Physical Examination:
-Thorough ear, nose, and throat (ENT) examination
-Assess nasal airflow by occluding one nostril at a time
-Visualize the posterior pharynx for postnasal drip and adenoid tissue if visible
-Palpate the neck for lymphadenopathy
-Assess for adenoid facies and dental malocclusion
-Evaluate tonsillar size
-Assess tympanic membranes for OME.
Investigations:
-Lateral neck X-ray: commonly used to visualize the adenoid pad and assess the degree of airway obstruction
-measurement of adenoid-nasopharyngeal ratio
-Flexible nasopharyngoscopy: provides direct visualization of the adenoid size and airway patency
-considered the gold standard by some
-Polysomnography (PSG): essential for diagnosing and quantifying the severity of sleep-disordered breathing, including obstructive sleep apnea (OSA).
-Laboratory tests are generally not indicated unless ruling out other conditions or investigating recurrent infections.
Differential Diagnosis:
-Other causes of nasal obstruction in children include allergic rhinitis, chronic sinusitis, nasal polyps, foreign body in the nose, choanal atresia (congenital), and nasal tumors (rare)
-Differential diagnoses for SDB include primary snoring, central sleep apnea, and other conditions affecting upper airway function.

Management

Initial Management:
-Management depends on the severity of symptoms and the impact on the child's quality of life
-For mild symptoms without significant SDB, conservative management may be considered
-For moderate to severe obstruction or confirmed SDB, surgical intervention is often recommended.
Medical Management:
-Primarily for associated conditions like allergic rhinitis or chronic sinusitis
-Nasal corticosteroids (e.g., fluticasone, mometasone) can reduce inflammation and improve nasal airflow
-Antihistamines may be used if allergic rhinitis is present
-Antibiotics are indicated for acute bacterial sinusitis but not for hypertrophy itself
-Montelukast has shown some benefit in reducing adenoid size in certain studies but is not a first-line therapy.
Surgical Management:
-Adenoidectomy is the surgical removal of the adenoid tissue
-It is indicated for significant nasal obstruction, recurrent sinopulmonary infections attributed to adenoid hypertrophy, and obstructive sleep apnea due to adenoid enlargement
-It can be performed alone or in conjunction with tonsillectomy
-Techniques include curettage, electrocautery, coblation, and microdebrider-assisted adenoidectomy.
Supportive Care:
-For children with SDB, appropriate positioning during sleep (e.g., elevating the head of the bed) may offer some relief
-Close monitoring for signs of respiratory distress, especially postoperatively, is crucial
-Nutritional support is important for children with feeding difficulties related to nasal obstruction.

Complications

Early Complications:
-Bleeding (hematemesis, epistaxis) is the most common early complication, usually minor but can be severe
-Pain, fever, nausea, vomiting, and dehydration
-Nasal regurgitation of food if palate injury occurs
-Injury to surrounding structures (e.g., Eustachian tube, pharyngeal wall).
Late Complications:
-Regrowth of adenoid tissue leading to recurrence of symptoms
-Velopharyngeal insufficiency (VPI), resulting in hypernasal speech, is rare but more common in children with underlying palatal abnormalities or those undergoing simultaneous tonsillectomy
-Chronic nasal congestion or sinusitis if underlying allergies or anatomical issues persist
-Persistent SDB if residual obstruction or other contributing factors remain.
Prevention Strategies:
-Meticulous surgical technique during adenoidectomy to minimize trauma to surrounding structures
-Careful patient selection for surgery
-Postoperative care including adequate hydration and pain management
-Early recognition and management of bleeding episodes
-Identifying and addressing contributing factors like allergies or obesity.

Prognosis

Factors Affecting Prognosis:
-Severity of adenoid hypertrophy and associated SDB
-Presence of comorbidities (e.g., obesity, syndromic conditions)
-Adherence to medical management if indicated
-Surgical success rates
-Long-term follow-up and management of residual or recurrent issues.
Outcomes:
-Adenoidectomy generally provides significant improvement in nasal breathing, snoring, and resolution of SDB in most children
-Long-term outcomes are generally good, with a significant reduction in SDB-related symptoms and improved quality of life
-However, some children may experience recurrence of symptoms over time.
Follow Up:
-Postoperative follow-up is essential to monitor for bleeding, pain, and signs of VPI
-Long-term follow-up may be necessary for children with persistent SDB, recurrent infections, or other ongoing concerns
-Assessment of breathing, sleep quality, and recurrent sinopulmonary infections should be part of routine pediatric care for children with a history of adenoid hypertrophy.

Key Points

Exam Focus:
-Adenoid hypertrophy is a major cause of nasal obstruction and SDB in children
-Clinical suspicion should be high in children with mouth breathing, snoring, and restless sleep
-Lateral neck X-ray and flexible nasopharyngoscopy are key diagnostic tools for assessing the adenoid
-Polysomnography is crucial for diagnosing and grading SDB
-Adenoidectomy is the definitive treatment for symptomatic cases.
Clinical Pearls:
-Always consider adenoid hypertrophy in children with persistent mouth breathing and snoring
-Remember that enlarged tonsils do not always correlate with the degree of adenoid hypertrophy
-Even mild adenoid hypertrophy can significantly disrupt sleep architecture
-Be aware of the potential for velopharyngeal insufficiency post-adenoidectomy, especially in at-risk children.
Common Mistakes:
-Attributing all snoring to simple adenoid hypertrophy without investigating for underlying OSA
-Relying solely on lateral neck X-ray without clinical correlation or considering nasopharyngoscopy for definitive assessment
-Failing to perform polysomnography in cases of suspected moderate to severe SDB
-Delaying surgical intervention when symptoms significantly impact a child's quality of life or development.