Overview

Definition:
-Anterior epistaxis refers to bleeding originating from the anterior part of the nasal cavity, most commonly from Kiesselbach's plexus (the Little's area) located on the anterior nasal septum
-It is the most frequent type of nosebleed encountered in pediatrics
-The management of anterior epistaxis in children often involves conservative measures including topical vasoconstrictors and, if necessary, cautery.
Epidemiology:
-Epistaxis is a common emergency in pediatric practice, with an incidence that peaks between ages 2-10 years
-Approximately 50% of children will experience at least one nosebleed before the age of 15
-While most cases are self-limiting and benign, recurrent or severe bleeding can be a source of parental anxiety and require medical intervention
-Dry air, nasal trauma, and upper respiratory infections are common triggers.
Clinical Significance:
-Effective management of anterior epistaxis is crucial in pediatric care to control bleeding, prevent complications like anemia or hypovolemic shock in rare severe cases, and reduce patient and parental distress
-Understanding the role of topical vasoconstrictors and the indications and techniques for nasal cautery is essential for pediatric residents preparing for DNB and NEET SS examinations, as these are core management principles.

Clinical Presentation

Symptoms:
-Bright red blood emerging from one or both nares
-Child may swallow blood, leading to nausea or vomiting
-Restlessness and crying due to anxiety and blood loss
-In severe cases, pallor, tachycardia, and hypotension may be present
-History of recent trauma, dry environment, or URI is often elicited.
Signs:
-Visible blood trickling from the anterior nasal vestibule
-Nasal mucosa may appear dry, inflamed, or crusted
-Gentle pressure on the nasal alae may control bleeding
-In persistent bleeding, active arterial spurt may be observed from the septum
-Examination should assess for signs of hypovolemia.
Diagnostic Criteria:
-Diagnosis is primarily clinical, based on patient history and direct visualization of bleeding from the anterior nasal cavity
-There are no specific laboratory or imaging criteria for diagnosing simple anterior epistaxis
-However, underlying etiologies for recurrent or severe epistaxis may warrant further investigation.

Diagnostic Approach

History Taking:
-Duration and severity of bleeding
-Frequency of episodes
-Presence of associated symptoms like fever or malaise
-History of trauma, nose picking, or foreign body
-Medication use (aspirin, NSAIDs, anticoagulants)
-History of bleeding disorders or familial bleeding diathesis
-Recent upper respiratory infections or allergies
-Environmental factors (humidity).
Physical Examination:
-Vital signs assessment (heart rate, blood pressure, respiratory rate)
-Examination of the anterior nasal septum for the bleeding source (Kiesselbach's plexus)
-Examination of the nasal mucosa for dryness, inflammation, or ulceration
-Assessment for nasal foreign bodies
-Gentle palpation of the neck for lymphadenopathy
-In cases of significant blood loss, a complete physical examination to assess for pallor and signs of shock is vital.
Investigations:
-For uncomplicated anterior epistaxis, no routine investigations are typically required
-In cases of recurrent severe epistaxis, or suspicion of underlying coagulopathy: Complete Blood Count (CBC) to assess for anemia or thrombocytopenia
-Coagulation profile (PT, aPTT, INR) to rule out clotting factor deficiencies
-Platelet function tests if indicated
-Nasal endoscopy or rhinoscopy may be performed by a specialist to identify rarer causes.
Differential Diagnosis:
-Posterior epistaxis (often more severe and bilateral)
-Nasal foreign body
-Nasal tumor (rare)
-Sinusitis
-Trauma to the face or nose
-Bleeding from pharyngeal or esophageal sources (swallowed blood)
-Bleeding disorders.

Management

Initial Management:
-Position the child upright and leaning forward to prevent aspiration of blood
-Apply direct pressure to the soft, anterior part of the nose for 10-15 minutes continuously
-Encourage nasal breathing and calm the child
-Pack the anterior nares with sterile gauze or cotton pledgets soaked in a vasoconstrictor if available.
Topical Vasoconstrictors:
-Topical vasoconstrictors, such as oxymetazoline (e.g., 0.05% nasal spray) or dilute epinephrine (1:10,000 or 1:100,000 solution applied to gauze), can be used to reduce blood flow to the nasal mucosa
-These are applied to gauze pledgets and inserted into the anterior nostril
-Their effect is typically rapid, causing local vasoconstriction
-They are particularly useful as an adjunct to pressure or prior to cautery.
Cautery:
-Chemical cautery using silver nitrate sticks is the mainstay for controlling persistent anterior epistaxis when direct pressure and vasoconstrictors are insufficient
-The bleeding site on the nasal septum should be identified and, if possible, anesthetized with a topical anesthetic spray (e.g., lidocaine with epinephrine)
-The silver nitrate stick is then applied gently to the bleeding vessel for a short duration (5-10 seconds), creating a superficial burn and sealing the vessel
-Electrocautery may be used in select cases by an otolaryngologist
-It is essential to avoid cauterizing both sides of the nasal septum to prevent septal perforation.
Nasal Packing:
-If bleeding persists despite cautery, anterior nasal packing with hemostatic agents (e.g., absorbable gelatin sponge, oxidized regenerated cellulose) or conventional gauze packing may be required
-For very severe or posterior bleeding, posterior packing or balloon catheters may be necessary, usually performed by a specialist.

Complications

Early Complications:
-Recurrence of bleeding
-Pain and discomfort from packing or cautery
-Nasal obstruction and difficulty breathing
-Infection at the cautery site
-Septal hematoma formation (if cautery is too deep or applied bilaterally).
Late Complications:
-Septal perforation (most common with bilateral cautery or repeated trauma)
-Chronic rhinitis or sinusitis
-Nasal crusting and synechiae (nasal adhesions)
-Anemia due to chronic blood loss (rare with anterior epistaxis).
Prevention Strategies:
-Humidification of the environment, especially during dry seasons
-Saline nasal sprays or gels to keep the nasal mucosa moist
-Discouraging nose picking
-Prompt treatment of nasal infections
-Careful technique during cautery to avoid bilateral septal application.

Prognosis

Factors Affecting Prognosis:
-The underlying cause of epistaxis
-The severity and frequency of bleeding
-Presence of coagulopathies or other systemic diseases
-Adherence to post-treatment care recommendations.
Outcomes:
-Most cases of anterior epistaxis in children are managed successfully with conservative measures, topical vasoconstrictors, and cautery
-Recurrence rates vary, but many children outgrow epistaxis by adolescence
-The prognosis for resolving bleeding is generally excellent with appropriate management.
Follow Up:
-For simple, isolated episodes, no specific follow-up may be needed beyond ensuring bleeding has stopped
-For recurrent or severe epistaxis, or if underlying etiologies are suspected, follow-up with a pediatrician or ENT specialist may be required to monitor for complications and investigate further
-Patients should be advised to avoid blowing their nose forcefully and to use saline nasal spray for a few days post-treatment.

Key Points

Exam Focus:
-Kiesselbach's plexus is the most common source of anterior epistaxis
-Topical vasoconstrictors (oxymetazoline, epinephrine) and silver nitrate cautery are primary management tools
-Avoid bilateral septal cautery to prevent perforation
-Management emphasizes pressure, topical agents, and cautery, with packing as a secondary measure.
Clinical Pearls:
-Always position the child leaning forward to prevent aspiration
-Continuous, firm pressure for 10-15 minutes is crucial before considering other interventions
-Topical lidocaine with epinephrine can provide both anesthesia and further vasoconstriction before cautery
-Ensure adequate hemostasis before discharge, and educate parents on warning signs of recurrence.
Common Mistakes:
-Failing to apply adequate continuous pressure
-Bimanual compression of the nasal bridge instead of applying pressure to the soft anterior alae
-Over-cauterization or bilateral cautery leading to septal perforation
-Discharging patients with active bleeding or without clear instructions for home care.