Overview

Definition:
-Spondylolysis is a stress fracture or defect in the pars interarticularis of a vertebra, most commonly L5
-Spondylolisthesis is the forward slippage of one vertebra over the one below it, often a consequence of bilateral spondylolysis
-Both are common causes of low back pain in active adolescents.
Epidemiology:
-Spondylolysis affects approximately 5-7% of the general population, with higher prevalence (up to 15-20%) in athletes involved in sports with repetitive hyperextension and rotation, such as gymnastics, football, and weightlifting
-Spondylolisthesis occurs in about 3-5% of individuals with spondylolysis.
Clinical Significance:
-Understanding the distinction and relationship between spondylolysis and spondylolisthesis is crucial for accurate diagnosis and effective management in pediatric patients
-Missed or delayed diagnosis can lead to chronic pain, functional limitations, and potentially neurological deficits, impacting a young athlete's career and quality of life.

Clinical Presentation

Symptoms:
-Dull, aching low back pain, often exacerbated by activity, especially hyperextension or twisting motions
-Pain may radiate to the buttocks or thighs
-Hamstring tightness is common
-In some cases, neurological symptoms like leg weakness or numbness may occur if nerve roots are compressed.
Signs:
-Tenderness over the affected spinous process or paraspinal muscles
-Palpable step-off at the lumbosacral junction in higher-grade spondylolisthesis
-Limited range of motion in the lumbar spine, particularly extension
-Positive straight leg raise test
-Tight hamstrings are a frequent finding.
Diagnostic Criteria:
-There are no formal diagnostic criteria for spondylolysis/spondylolisthesis in the same way as some infectious diseases
-Diagnosis relies on a combination of suggestive clinical presentation, physical examination findings, and characteristic radiographic evidence.

Diagnostic Approach

History Taking:
-Detailed history of the onset and duration of pain
-Specific activities that aggravate or relieve pain
-History of repetitive sports participation
-Any prior trauma to the back
-Red flags include bowel/bladder dysfunction, fever, weight loss, or nocturnal pain, which suggest other serious pathologies.
Physical Examination:
-Assess gait and posture
-Palpate the lumbar spine for tenderness and step-offs
-Evaluate lumbar spine range of motion (flexion, extension, lateral bending, rotation)
-Assess hamstring flexibility
-Perform neurological examination including motor strength, sensation, and reflexes in the lower extremities
-Perform tests like the prone hyperextension test and straight leg raise test.
Investigations:
-Initial imaging typically involves plain radiography (AP, lateral, oblique views of the lumbar spine)
-Oblique views are crucial for visualizing the "Scottie dog" sign of spondylolysis (a fracture in the pars interarticularis)
-Lateral views assess for slippage (spondylolisthesis)
-If plain radiographs are equivocal or neurological symptoms are present, MRI is indicated to assess for associated soft tissue injury, nerve root compression, or bone marrow edema
-CT scan can provide more detailed bone anatomy, especially for complex fractures.
Differential Diagnosis: Muscular strain, lumbar disc herniation, vertebral body fractures (other than pars), Scheuermann's kyphosis, scoliosis, spinal infections (osteomyelitis, discitis), tumors, inflammatory arthropathies, and hip pathology.

Management

Initial Management:
-Discontinuation of aggravating activities
-Relative rest
-Pain control with analgesics
-Modalities like ice or heat can provide symptomatic relief
-Education about the condition and prognosis is vital.
Medical Management:
-Conservative management is the mainstay
-It includes physical therapy focusing on core strengthening, flexibility exercises for hamstrings and hip flexors, and postural correction
-Non-steroidal anti-inflammatory drugs (NSAIDs) can be used for pain and inflammation control, typically for short durations
-Activity modification is key, with gradual return to sports as symptoms improve.
Surgical Management:
-Surgery is generally reserved for cases with persistent, debilitating pain despite conservative management, or for those with progressive neurological deficits or high-grade slips (grades III-IV)
-Procedures include pars repair (in select cases of active lysis) or spinal fusion (posterolateral fusion or interbody fusion) to stabilize the segment
-The goal is to relieve pain and prevent further slippage.
Supportive Care:
-Psychological support for young athletes struggling with pain and activity limitations
-Nutritional assessment to ensure adequate calcium and Vitamin D intake for bone health
-Close monitoring for recurrence or progression of symptoms.

Complications

Early Complications:
-Infection, bleeding, nerve root injury, dural tear, non-union of pars repair, or pseudarthrosis of fusion
-Persistent pain is a common "complication" of conservative management if not adhered to.
Late Complications:
-Chronic low back pain, degenerative disc disease at adjacent levels (if fusion is performed), adjacent segment disease, radiculopathy, and spinal stenosis in severe or untreated cases
-Chronic pain can significantly affect psychological well-being and participation in physical activities.
Prevention Strategies:
-Proper training techniques in sports involving hyperextension and rotation
-Gradual increase in training intensity and duration
-Adequate warm-up and cool-down routines
-Strengthening of core and back muscles
-Encouraging proper posture and biomechanics
-Avoiding overtraining.

Prognosis

Factors Affecting Prognosis:
-Severity of the slip (grade of spondylolisthesis), presence of bilateral pars defects, persistence of pain, patient compliance with conservative treatment, and surgical success
-Younger age at diagnosis may portend a better prognosis for recovery.
Outcomes:
-Most adolescents with spondylolysis and low-grade spondylolisthesis (grades I-II) can return to full activity with conservative management, though some may experience intermittent pain
-Surgical outcomes for selected patients with persistent pain or significant instability are generally good, with pain relief and return to sports.
Follow Up:
-Regular follow-up with orthopedic specialists is recommended, particularly during periods of return to sport
-Imaging may be repeated if symptoms recur or worsen
-Long-term monitoring for adjacent segment degeneration is important, especially after fusion procedures.

Key Points

Exam Focus:
-The "Scottie dog" sign on oblique radiographs is pathognomonic for spondylolysis
-Spondylolisthesis is slippage of one vertebra over another, often due to bilateral spondylolysis
-Conservative management with rest, physical therapy, and NSAIDs is the first line of treatment
-Surgical intervention is reserved for refractory pain or neurological deficits
-Common levels are L5-S1 and L4-L5.
Clinical Pearls:
-Always consider spondylolysis/spondylolisthesis in an adolescent with persistent, activity-related low back pain
-Tight hamstrings are a classic finding
-Don't miss the oblique view on X-rays
-it's your best friend for spotting the pars defect
-MRI is essential for evaluating neural involvement.
Common Mistakes:
-Dismissing adolescent back pain as simple muscle strain without adequate investigation
-Relying solely on AP/lateral X-rays and missing oblique views for spondylolysis
-Inadequate conservative management duration before considering surgery
-Underestimating the psychological impact of chronic pain on young athletes.