Overview

Definition:
-Blount disease, also known as tibia vara, is a developmental disorder characterized by progressive posteromedial bowing of the tibia
-It results from abnormal growth at the medial aspect of the proximal tibial physis, leading to a varus deformity of the knee and tibia.
Epidemiology:
-It is more common in obese children and those who walk at an early age
-Early-onset Blount disease typically presents before age 4 and is often bilateral
-Late-onset Blount disease usually affects adolescents and is often unilateral.
Clinical Significance:
-Untreated Blount disease can lead to significant pain, gait abnormalities, osteoarthritis, and functional limitations, impacting a child's quality of life and long-term skeletal health
-Early diagnosis and appropriate management are crucial.

Clinical Presentation

Symptoms:
-Progressive bowing of the legs or inward bowing of the knees
-Gait disturbance, often described as a waddling or antalgic gait
-Pain in the knee or leg, particularly with activity
-Difficulty with prolonged standing or walking
-Unequal leg lengths may develop over time.
Signs:
-Visible varus deformity of the knee and tibia
-Medial joint line opening on examination
-Palpable tenderness over the medial proximal tibia
-Increased femorotibial angle
-Overweight or obese child
-Associated internal tibial torsion may be present.
Diagnostic Criteria:
-Diagnosis is primarily based on clinical examination and radiographic findings
-Radiographic criteria include the metaphyseal-diaphyseal angle (MDT angle) and the medial proximal tibial angle (MPTA)
-An MDT angle > 11 degrees and an MPTA > 8 degrees in infants/young children, or > 3 degrees in older children, are highly suggestive of Blount disease.

Diagnostic Approach

History Taking:
-Age of onset of bowing
-Progression of deformity
-Presence of pain and its character
-Gait abnormalities
-Family history of limb deformities
-Associated medical conditions, especially obesity
-Age of ambulation
-Activity level.
Physical Examination:
-Assess the overall alignment of the lower extremities
-Measure the degree of varus deformity at the knee
-Evaluate for internal tibial torsion
-Assess for leg length discrepancy
-Palpate for tenderness over the medial proximal tibia
-Assess range of motion of the knee and ankle joints.
Investigations:
-Weight-bearing anteroposterior (AP) and lateral radiographs of the entire tibia and femur
-Standing AP radiographs of the lower extremities are essential for assessing true alignment
-Obtain oblique views if needed to visualize the physis
-MRI may be useful in equivocal cases or to assess physeal integrity
-Measuring the femorotibial angle and the proximal tibial angle on X-rays is key.
Differential Diagnosis:
-Physiological bow legs (common in toddlers)
-Rickets (metabolic bone disease)
-Trauma to the proximal tibial physis
-Other congenital or genetic syndromes causing limb malformation
-Osteochondroma of the proximal tibia
-Fibrous dysplasia.

Management

Initial Management:
-Conservative management is typically the first line of treatment for early-onset Blount disease in younger children with mild deformities
-Weight loss is paramount for obese children
-Bracing may be considered for mild to moderate deformities.
Medical Management:
-Primarily focused on weight management and addressing any underlying metabolic issues (e.g., rickets, though rare as a cause of Blount disease)
-No specific pharmacotherapy for Blount disease itself.
Surgical Management:
-Indications for surgery include progressive deformity, significant pain, failure of conservative management, and functional impairment
-Options include: Hemiepiphysiodesis of the medial proximal tibia for younger children with remaining growth potential
-Osteotomy procedures, such as a lateral opening wedge osteotomy of the proximal tibia or a valgus osteotomy of the distal femur, for older children or those with severe deformities.
Supportive Care:
-Physical therapy to improve gait and strength
-Pain management with NSAIDs if necessary
-Orthotics or bracing may be used as adjuncts
-Close monitoring of weight and growth is essential.

Complications

Early Complications:
-Wound infection
-Nerve or vascular injury during surgery
-Non-union or malunion of osteotomy
-Compartment syndrome.
Late Complications:
-Progression of deformity despite treatment
-Osteoarthritis of the knee due to abnormal joint loading
-Leg length discrepancy
-Recurrence of Blount disease
-Persistent pain and functional limitation.
Prevention Strategies:
-Early identification and intervention
-Aggressive weight management in at-risk children
-Appropriate surgical timing and technique
-Close follow-up to monitor for recurrence or progression.

Prognosis

Factors Affecting Prognosis:
-Age at diagnosis and treatment
-Severity of the deformity
-Degree of physeal involvement
-Compliance with weight management and post-operative care
-Type of treatment employed.
Outcomes:
-With early and appropriate management, outcomes can be excellent, leading to normalized leg alignment and resolution of symptoms
-Late diagnosis or aggressive forms can lead to long-term functional deficits and early-onset osteoarthritis.
Follow Up:
-Regular clinical and radiographic follow-up is crucial, especially after surgical intervention
-This monitoring continues until skeletal maturity to ensure deformity correction is maintained and no complications arise
-Long-term follow-up may be needed for degenerative changes.

Key Points

Exam Focus:
-Blount disease is a progressive posteromedial bowing of the tibia due to abnormal physeal growth
-Differentiate early-onset vs
-late-onset
-Key radiographic markers: MDT angle and MPTA
-Management depends on age and severity: conservative for mild/early, surgical for severe/late.
Clinical Pearls:
-Always suspect Blount disease in obese children presenting with progressive bow legs
-Weight loss is a cornerstone of non-operative management
-Consider early surgical intervention in young children with significant or rapidly progressing deformity
-Accurate radiographic assessment with standing films is essential.
Common Mistakes:
-Confusing Blount disease with physiological bow legs in young children
-Delaying surgical intervention in cases of progressive deformity
-Inadequate radiographic assessment (e.g., not using standing films)
-Neglecting weight management as a critical component of treatment.