Overview

Definition:
-Fever is a temporary increase in body temperature above the normal range of 37°C (98.6°F)
-In children, a rectal temperature of 38°C (100.4°F) or higher is generally considered a fever
-Fever is a symptom, not an illness itself, and is often a sign that the body is fighting an infection or illness.
Epidemiology:
-Fever is one of the most common reasons parents seek medical attention for their children
-It is estimated that over 30% of children under 3 years of age will have at least one episode of fever annually
-The likelihood of serious bacterial infection decreases significantly with age.
Clinical Significance:
-Understanding when to seek medical care for a febrile child is crucial for timely diagnosis and management of potentially serious conditions
-It helps differentiate between self-limiting viral illnesses and conditions requiring urgent medical intervention, impacting patient outcomes and reducing healthcare burden.

Age Considerations

Infants Under 3 Months:
-Fever in infants younger than 3 months (12 weeks) is always a cause for concern and requires immediate medical evaluation
-Their immune systems are immature, and serious bacterial infections can progress rapidly.
Infants 3 To 6 Months:
-Fever in this age group warrants prompt medical attention, especially if the temperature is high or the infant appears unwell
-While less critical than younger infants, the risk of serious infection remains.
Older Infants And Children: For older infants and children, the approach to fever is more nuanced, focusing on the child's overall well-being, behavior, and associated symptoms rather than just the temperature reading.

Clinical Presentation

Symptoms:
-Elevated body temperature
-Irritability or lethargy
-Decreased activity and playfulness
-Poor feeding or decreased fluid intake
-Vomiting or diarrhea
-Cough, runny nose, or sore throat
-Rash
-Seizures (febrile seizures)
-Difficulty breathing.
Signs:
-High temperature on thermometer
-Warm skin
-Red cheeks
-Flushed appearance
-Increased heart rate and respiratory rate
-Signs of dehydration (dry mouth, sunken eyes, reduced urination)
-Lethargy or unresponsiveness.
Red Flags For Immediate Care:
-Fever in an infant less than 3 months old
-Temperature of 104°F (40°C) or higher
-Fever lasting more than 3 days
-Child appears very ill, lethargic, or difficult to wake
-Stiff neck or severe headache
-Difficulty breathing or shortness of breath
-Persistent vomiting or diarrhea
-Signs of dehydration
-Rash that doesn't fade when pressed
-Seizure
-Complains of severe pain.

Diagnostic Approach

History Taking:
-Duration and pattern of fever
-Associated symptoms (cough, vomiting, rash, etc.)
-Child's activity level and behavior
-Fluid intake and urine output
-Recent exposures to illness
-Vaccination status
-Any chronic medical conditions or medications
-History of febrile seizures.
Physical Examination:
-General appearance (alertness, comfort level, activity)
-Vital signs (temperature, heart rate, respiratory rate, blood pressure)
-Examination of ears, nose, throat, and lungs
-Assessment for rash
-Palpation of abdomen and lymph nodes
-Neurological assessment (mental status, neck stiffness).
Investigations:
-Complete blood count (CBC) to assess for infection and inflammation
-Blood cultures to identify bacteria in the bloodstream
-Urine culture to detect urinary tract infection
-Chest X-ray if pneumonia is suspected
-Lumbar puncture (spinal tap) to rule out meningitis
-Viral testing (e.g., influenza, RSV) may be considered based on symptoms and local epidemiology
-Swabs for strep throat or other rapid antigen detection tests.
Differential Diagnosis:
-Viral infections (common cold, influenza, gastroenteritis)
-Bacterial infections (otitis media, pneumonia, urinary tract infection, meningitis, sepsis)
-Kawasaki disease
-Other inflammatory conditions.

Management

Home Care For Mild Fever:
-Encourage fluid intake to prevent dehydration
-Dress the child in light clothing and keep the room at a comfortable temperature
-Do not over-bundle
-Administer antipyretics as recommended by a healthcare provider (e.g., acetaminophen or ibuprofen for children over 6 months)
-Monitor temperature and symptoms closely
-Provide rest.
When To Seek Medical Care:
-Refer to the "Red Flags for Immediate Care" section
-Always consult a pediatrician if you are concerned about your child's fever or overall condition
-Infants under 3 months with any fever need immediate evaluation
-Fever above 104°F (40°C) or fever lasting more than 3 days warrants a doctor's visit.
Medical Management:
-Treatment of the underlying cause
-Antipyretics (acetaminophen, ibuprofen) for symptom relief
-Antibiotics if a bacterial infection is diagnosed
-Antiviral medications for specific viral infections like influenza
-Hospitalization for severe illness, dehydration, or suspected sepsis/meningitis.
Supportive Care:
-Adequate hydration is paramount
-Rest is important for recovery
-Close monitoring of vital signs and symptoms by parents and healthcare providers
-Education for parents on fever management and warning signs.

Complications

Early Complications:
-Dehydration
-Febrile seizures (usually benign and self-limiting, but can be frightening)
-Worsening of underlying condition.
Late Complications:
-Rarely, untreated or inadequately treated serious infections can lead to long-term sequelae such as neurological damage, organ damage, or chronic illness
-Delayed diagnosis of conditions like meningitis or sepsis can be life-threatening.
Prevention Strategies:
-Promote good hygiene practices (handwashing)
-Ensure children are up-to-date on vaccinations
-Promptly address symptoms of illness
-Seek timely medical care for concerning fever presentations to prevent complications from serious infections.

Key Points

Exam Focus:
-Fever in neonates (< 28 days) is a medical emergency
-always admit and investigate
-Differentiating viral from bacterial causes is crucial
-Red flag symptoms for immediate evaluation are key for DNB/NEET SS scenarios
-Age-appropriate antipyretic dosing and indications are important.
Clinical Pearls:
-Trust your parental instinct
-A child's behavior and overall appearance are often more important than the exact temperature reading
-For infants under 3 months, any fever requires urgent medical attention regardless of other symptoms
-Avoid aspirin in children due to the risk of Reye's syndrome.
Common Mistakes:
-Over-reliance on temperature alone without assessing the child's overall well-being
-Underestimating the significance of fever in young infants
-Inappropriate use of antibiotics for viral infections
-Delaying medical evaluation for red flag symptoms.