Overview

Definition:
-Foreign body aspiration in toddlers refers to the inhalation of an object into the tracheobronchial tree, most commonly occurring between 6 months and 3 years of age
-Unilateral wheezing is a classic, though not universally present, sign suggesting a focal obstruction in one lung or bronchus.
Epidemiology:
-It is a leading cause of accidental death in young children
-Common aspirated objects include food items (nuts, seeds, popcorn, grapes) and small toys
-Unilateral wheezing is reported in approximately 50-70% of cases, often persistent and localized.
Clinical Significance:
-Prompt diagnosis and management are crucial to prevent serious complications such as pneumonia, atelectasis, lung abscess, and even respiratory failure
-Inadequate evaluation or delayed diagnosis can lead to significant morbidity and mortality, making its recognition vital for pediatricians and residents preparing for DNB and NEET SS.

Clinical Presentation

Symptoms:
-Sudden onset of choking, gagging, or coughing episode
-Subsequent development of persistent, localized wheezing (unilateral)
-Decreased breath sounds on one side
-Recurrent pneumonia or bronchitis episodes
-Dyspnea and tachypnea
-Possible hemoptysis
-Fever may develop if secondary infection occurs.
Signs:
-Unilateral decreased breath sounds
-Unilateral wheezing, often inspiratory or expiratory
-Increased work of breathing
-Localized crackles or rhonchi
-Possible cyanosis in severe cases
-Fever if infection is present
-Inability to vocalize clearly if the object is in the trachea.
Diagnostic Criteria:
-No specific diagnostic criteria exist
-diagnosis is primarily clinical, supported by imaging and direct visualization
-A history of a witnessed or suspected choking event, followed by persistent unilateral wheezing, is highly suggestive.

Diagnostic Approach

History Taking:
-Detailed history of the inciting event: onset, timing, nature of the object (if known), and symptoms
-Inquire about any preceding respiratory illness or other conditions
-Ask about parental observations of choking, gagging, or changes in breathing pattern
-Explore risk factors for aspiration (e.g., feeding practices, toys within reach).
Physical Examination:
-Thorough assessment of respiratory status: respiratory rate, heart rate, oxygen saturation, work of breathing
-Auscultate lung fields systematically, noting the presence, location, and type of wheezing and breath sounds
-Palpate chest for symmetry of expansion and tactile fremitus
-Assess for any signs of distress or cyanosis
-Inspect the oropharynx for any visible foreign body.
Investigations:
-Chest X-ray (PA and lateral views): may show hyperinflation of the affected lung, atelectasis, or a visible radiopaque foreign body
-However, up to 50% of X-rays can be normal, especially with radiolucent objects
-Fluoroscopy can reveal dynamic air trapping or mediastinal shift
-CT scan of the chest with expiratory views: superior sensitivity for detecting air trapping and occult foreign bodies, especially radiolucent ones
-Bronchoscopy: the gold standard for diagnosis and simultaneous removal of the foreign body
-It allows direct visualization of the tracheobronchial tree.
Differential Diagnosis:
-Asthma: typically bilateral wheezing, episodic, responds to bronchodilators
-Bronchiolitis: diffuse wheezing, usually in younger infants, often viral prodrome
-Pneumonia: fever, crackles, lobar consolidation, usually bilateral or diffuse
-Viral croup: stridor, barking cough, inspiratory wheeze
-Congenital airway anomalies: persistent symptoms from birth
-Bronchogenic cyst or other masses: may cause extrinsic compression.

Management

Initial Management:
-Immediate assessment of airway patency and respiratory status
-Administer supplemental oxygen to maintain saturation >94%
-If object is visible in the oropharynx and easily accessible, attempt removal cautiously
-If significant respiratory distress, consider positive pressure ventilation
-Definitive management is bronchoscopic removal.
Medical Management:
-Generally not indicated for acute foreign body aspiration itself, but supportive care is essential
-Bronchodilators (e.g., albuterol) may be tried for wheezing but are often ineffective if the obstruction is fixed
-Antibiotics are indicated if pneumonia or infection is suspected or develops.
Surgical Management:
-Bronchoscopy is the primary intervention for removal
-Rigid bronchoscopy is preferred due to its ability to provide ventilation and adequate visualization
-If bronchoscopy fails or complications arise, rigid bronchoscopy or even thoracotomy may be considered in rare, refractory cases.
Supportive Care:
-Continuous cardiorespiratory monitoring
-Maintain adequate hydration and nutrition
-Close observation for signs of respiratory compromise
-Management of secondary infections (e.g., pneumonia) with appropriate antibiotics and pulmonary toilet.

Complications

Early Complications:
-Complete airway obstruction leading to asphyxiation
-Laryngospasm and bronchospasm
-Pneumothorax due to barotrauma during ventilation
-Tracheobronchial perforation.
Late Complications:
-Post-obstructive pneumonia
-Lung abscess
-Atelectasis and bronchiectasis
-Granuloma formation around the foreign body
-Chronic cough and persistent wheezing
-Hemoptysis
-Bronchiolitis obliterans.
Prevention Strategies:
-Educate parents about choking hazards and safe food preparation for toddlers
-Avoid feeding small, round, or hard foods to young children
-Ensure toys are age-appropriate and free of small detachable parts
-Supervise young children during meals and play.

Prognosis

Factors Affecting Prognosis:
-The type and location of the foreign body
-The duration of airway obstruction
-The promptness of diagnosis and intervention
-The presence and severity of complications like infection or lung damage
-The skill of the endoscopist.
Outcomes:
-With timely diagnosis and bronchoscopic removal, the prognosis is generally excellent, with complete resolution of symptoms
-Delayed diagnosis or complications can lead to long-term respiratory sequelae, including chronic lung disease.
Follow Up:
-Follow-up chest X-rays may be needed to assess resolution of atelectasis or pneumonia
-Patients with residual symptoms or complications may require ongoing pulmonary assessment, including PFTs if age-appropriate, and management for conditions like bronchiectasis or reactive airway disease.

Key Points

Exam Focus:
-Remember that a normal chest X-ray does NOT rule out foreign body aspiration
-Unilateral wheeze in a toddler with a history of choking is a strong indicator
-Bronchoscopy is both diagnostic and therapeutic
-Radiopaque foreign bodies are easier to visualize on X-ray.
Clinical Pearls:
-Always consider foreign body aspiration in a toddler with unexplained unilateral wheezing or recurrent pneumonia
-Even without a witnessed choking episode, it should remain in the differential
-Consider expiratory CT scans if initial investigations are negative but suspicion remains high.
Common Mistakes:
-Dismissing symptoms as asthma without considering foreign body aspiration
-Relying solely on chest X-ray findings
-Delaying bronchoscopy in the presence of high clinical suspicion
-Failure to counsel parents on prevention strategies.