Overview

Definition:
-Neonatal resuscitation is a set of interventions performed immediately after birth to support infants who are not breathing spontaneously or who have inadequate ventilation
-It is a critical component of neonatal care aimed at preventing mortality and morbidity
-Temperature management is an integral part of resuscitation and post-resuscitation care to maintain normothermia, as neonates are particularly vulnerable to heat loss and cold stress.
Epidemiology:
-Approximately 10% of newborns require some form of resuscitation at birth, while about 1% require positive-pressure ventilation or chest compressions
-Prematurity, intrapartum events like meconium aspiration, and congenital anomalies are common reasons for requiring resuscitation
-Hypothermia is common in newborns due to immature thermoregulation and large surface area to mass ratio.
Clinical Significance:
-Effective neonatal resuscitation can prevent hypoxic-ischemic brain injury, organ damage, and death
-Maintaining normothermia is crucial as hypothermia increases metabolic rate, oxygen consumption, and the risk of intraventricular hemorrhage, hypoglycemia, and mortality
-Conversely, hyperthermia can also be detrimental
-Proper technique and prompt intervention are paramount for optimal outcomes and are frequently tested in DNB and NEET SS examinations.

Initial Assessment And Steps

Assessment At Birth:
-Assess breathing effort, muscle tone, and heart rate at birth
-If the infant is term, has good muscle tone, and is breathing or crying, routine care is provided
-If apneic or gasping, with poor muscle tone, positive-pressure ventilation (PPV) is indicated
-A heart rate below 100 bpm also requires PPV.
Positive Pressure Ventilation Ppv:
-Initiate PPV with a rate of 40-60 breaths per minute
-Ensure a good mask seal and watch for chest rise
-If the heart rate remains below 60 bpm despite effective PPV, consider chest compressions.
Chest Compressions:
-If the heart rate is less than 60 bpm despite 30 seconds of effective PPV, initiate chest compressions using a 3:1 compression-to-ventilation ratio (90 compressions: 30 breaths per minute)
-Continue until spontaneous circulation returns or the infant stabilizes.
Medications And Fluids:
-Epinephrine is the primary drug for bradycardia (HR < 60 bpm despite CPR)
-It is administered intravenously or intraosseously
-Volume expansion with normal saline may be considered for presumed hypovolemia
-Sodium bicarbonate, naloxone, and surfactant are used in specific circumstances.
Airway Management:
-For infants not responding to PPV, consider intubation for more effective ventilation, administration of medications, or management of airway obstruction
-Use of suctioning should be judicious and only if there is obvious obstruction.

Temperature Management

Importance Of Normothermia:
-Neonates have limited ability to regulate body temperature, making them susceptible to hypothermia and hyperthermia
-Maintaining a core body temperature between 36.5°C and 37.5°C is vital for metabolic stability, oxygen consumption, and reducing complications.
Prevention Of Heat Loss:
-Prevent heat loss by drying the infant immediately after birth, removing wet linen, placing the infant skin-to-skin with the mother, and covering with a dry blanket
-Use a radiant warmer for infants requiring resuscitation or separated from their mother.
Monitoring Temperature:
-Continuous temperature monitoring using a rectal or esophageal probe is recommended, especially for infants requiring resuscitation or those at risk for temperature instability
-Axillary and skin probes are less accurate for core temperature.
Management Of Hypothermia:
-For hypothermic infants (rectal temp < 36.5°C), gradually rewarm using a radiant warmer or incubator with controlled temperature settings
-Avoid rapid rewarming, which can cause complications
-Target a gradual increase of 0.5-1°C per hour.
Management Of Hyperthermia:
-Hyperthermia (rectal temp > 37.5°C) can occur due to excessive external heat or immaturity
-Reduce external heat sources, remove blankets, and promote evaporation
-In severe cases, a tepid sponge bath may be considered, but caution is advised to avoid chilling.

Resuscitation Algorithm And Guidelines

Neonatal Resuscitation Program Nrp:
-The Neonatal Resuscitation Program (NRP) guidelines, developed by the American Academy of Pediatrics and the American Heart Association, provide a standardized approach to neonatal resuscitation
-These guidelines are updated periodically based on the latest evidence.
Initial Steps In Algorithm:
-The NRP algorithm begins with the assessment of term gestation, muscle tone, and crying
-If any of these are absent, the infant requires PPV
-The algorithm then guides decisions on chest compressions and medications based on heart rate.
Steps For Inadequate Respiratory Effort:
-If the infant is apneic or gasping, PPV is initiated
-If the heart rate is <100 bpm, PPV is continued
-If the heart rate is <60 bpm despite 30 seconds of effective PPV, chest compressions are started
-If the heart rate is >60 bpm, PPV is continued.
Guidelines For Temperature Management:
-Current guidelines emphasize active warming for hypothermic infants and avoiding overheating
-Skin-to-skin contact and radiant warmers are key interventions for maintaining normothermia
-Monitoring is crucial for infants at risk.

Common Challenges And Pearls

Mask Seal And Ventilation:
-Achieving a good mask seal is critical for effective PPV
-Use the correct size mask and a C- or E-shaped hand position
-Chest rise is the primary indicator of effective ventilation.
Chest Compression Technique:
-Use the two-thumb encircling hand technique for infants, with compressions covering the lower third of the sternum
-Ensure adequate depth (approximately one-third of the anteroposterior chest diameter) and rate (100-120 compressions per minute).
Recognizing Bradycardia:
-Persistent bradycardia (HR < 60 bpm) despite effective PPV is an indication for chest compressions and epinephrine
-Careful monitoring of heart rate is essential.
Post Resuscitation Care:
-After successful resuscitation, continued monitoring of cardiorespiratory status, temperature, and glucose levels is crucial
-Therapeutic hypothermia may be indicated for neonates with hypoxic-ischemic encephalopathy, following specific protocols.
Team Communication:
-Effective communication among the resuscitation team is vital
-Clear roles, closed-loop communication, and debriefing after events improve outcomes and learning.

Key Points

Exam Focus:
-Understand the stepwise approach to neonatal resuscitation, indications for PPV, chest compressions, and medications
-Be familiar with the NRP algorithm and temperature management goals
-DNB and NEET SS often ask about specific heart rates triggering interventions.
Clinical Pearls:
-Always dry the baby first
-skin-to-skin contact is best for thermoregulation
-Chest rise is your guide for PPV efficacy
-If HR < 60 despite PPV, think compressions and Epi
-Temperature is a vital sign in neonates.
Common Mistakes:
-Inadequate mask seal leading to ineffective PPV
-Incorrect compression rate or depth
-Delayed initiation of chest compressions or epinephrine
-Overlooking temperature management or rapid rewarming
-Ineffective team communication.