Overview

Definition:
-Pediatric splenic injury refers to damage to the spleen, a vital organ in the upper left quadrant of the abdomen, typically resulting from blunt abdominal trauma
-Nonoperative management (NOM) aims to avoid splenectomy, preserving splenic function.
Epidemiology:
-Splenic injuries are the most common intra-abdominal injuries in children following blunt trauma, accounting for approximately 50% of such injuries
-They are most frequently caused by falls, bicycle accidents, and motor vehicle collisions
-Male children are more commonly affected
-Grade of injury dictates management and prognosis.
Clinical Significance:
-The spleen plays crucial roles in immune function (antibody production, opsonization) and red blood cell filtration
-Splenectomy in children significantly increases the risk of overwhelming post-splenectomy infection (OPSI), a potentially life-threatening complication
-Therefore, NOM is the preferred approach whenever feasible to preserve splenic function and reduce long-term morbidity.

Clinical Presentation

Symptoms:
-Abdominal pain, often localized to the left upper quadrant or radiating to the left shoulder (Kehr's sign)
-Abdominal distension
-Nausea and vomiting
-Signs of hypovolemic shock in severe cases: pallor, tachycardia, hypotension, altered mental status.
Signs:
-Tenderness in the left upper quadrant
-Guarding and rebound tenderness
-Palpable abdominal mass (less common)
-Bruising or ecchymosis over the left flank (flank abrasion sign)
-Signs of shock: hypotension, tachycardia, tachypnea
-Decreased breath sounds on the left due to diaphragmatic irritation or hemothorax.
Diagnostic Criteria:
-No specific diagnostic criteria exist
-diagnosis relies on clinical suspicion in a trauma setting and confirmation with imaging
-American Association for the Surgery of Trauma (AAST) organ injury scale is used to grade splenic injuries, guiding management decisions.

Diagnostic Approach

History Taking:
-Detailed mechanism of injury (blunt trauma, falls, sports, MVC)
-Age and weight of the child
-Vital signs at presentation
-Previous abdominal surgeries or medical conditions
-Medications (anticoagulants, NSAIDs).
Physical Examination:
-Assess for signs of trauma to the abdomen and chest
-Perform a thorough abdominal examination, including inspection for bruising, auscultation for bowel sounds, palpation for tenderness, guarding, and rebound
-Evaluate for signs of hypovolemic shock
-Assess for associated injuries.
Investigations:
-FAST (Focused Assessment with Sonography for Trauma) examination: Initial bedside ultrasound to detect free fluid in the abdomen and pelvis
-Computed Tomography (CT) scan of the abdomen and pelvis with intravenous contrast: The gold standard for diagnosing and grading splenic injuries
-It identifies lacerations, hematomas, and active extravasation
-Laboratory tests: Complete blood count (CBC) to assess for anemia and hemoconcentration
-coagulation profile
-blood type and crossmatch.
Differential Diagnosis:
-Gastric or duodenal perforation
-Pancreatic injury
-Renal injury
-Left lower lobe pneumonia
-Mesenteric injury
-Diaphragmatic rupture
-Rib fractures.

Management

Initial Management:
-Resuscitation with intravenous fluids (crystalloids, colloids) and blood products if hemodynamically unstable
-Maintain airway, breathing, and circulation (ABCs)
-Pain management
-Strict bed rest.
Nonoperative Management:
-Reserved for hemodynamically stable patients with confirmed splenic injury on imaging
-Serial abdominal examinations are crucial to monitor for signs of deterioration
-Hemodynamic stability is the key determinant
-Grade of injury (AAST Grade I-III often suitable for NOM
-Grade IV-V may require intervention)
-Absence of active contrast extravasation on CT scan.
Activity Restriction:
-Strict bed rest initially
-Gradual mobilization as tolerated
-Restrictions on contact sports and strenuous physical activity are essential to prevent re-injury and delayed bleeding
-Duration of restriction is typically 4-6 weeks for low-grade injuries and longer (up to 3-6 months) for higher grades or those requiring embolization
-Clear guidance on return to play is vital.
Supportive Care:
-Continuous hemodynamic monitoring
-Serial hemoglobin and hematocrit checks
-Adequate pain control
-Nutritional support as tolerated
-Prophylactic antibiotics are not routinely recommended unless there is an associated hollow viscus injury
-Pneumococcal and meningococcal vaccinations should be administered if splenectomy becomes necessary.

Complications

Early Complications:
-Hemorrhagic shock
-Hemoperitoneum
-Delayed splenic rupture (days to weeks after initial injury).
Late Complications:
-Overwhelming post-splenectomy infection (OPSI) if splenectomy is performed
-Pseudocyst formation
-Splenomegaly
-Chronic pain.
Prevention Strategies:
-Adherence to strict activity restriction protocols
-Close monitoring for signs of re-bleeding or deterioration
-Judicious use of splenectomy, opting for NOM and splenic artery embolization when appropriate.

Prognosis

Factors Affecting Prognosis:
-Grade of splenic injury
-Hemodynamic stability at presentation
-Presence of associated injuries
-Timeliness and appropriateness of management
-Patient's age and comorbidities.
Outcomes:
-Excellent outcomes with successful NOM, with preservation of splenic function and immune competence
-Higher grades of injury, especially those requiring embolization or rarely surgery, may have a slightly higher risk of complications
-Successful NOM rates in pediatric splenic trauma are high, often exceeding 90%.
Follow Up:
-Regular clinical follow-up is necessary to assess for resolution of symptoms and to guide return to normal activities
-Serial abdominal examinations are performed during hospitalization
-Outpatient follow-up may include imaging if there are concerns
-Clear discharge instructions regarding activity limitations and warning signs are critical.

Key Points

Exam Focus:
-NOM is preferred for hemodynamically stable pediatric splenic injuries
-AAST grading is crucial
-Serial abdominal exams are paramount in NOM
-Splenectomy significantly increases OPSI risk
-Activity restriction duration depends on injury grade.
Clinical Pearls:
-Always consider splenic injury in a child with blunt abdominal trauma, even with minimal external signs
-Kehr's sign is a classic indicator
-FAST exam can quickly identify free fluid
-CT scan is definitive for grading and planning management
-Embolization is a key NOM adjunct for higher-grade injuries.
Common Mistakes:
-Prematurely opting for splenectomy without considering NOM
-Inadequate monitoring of hemodynamically stable patients on NOM
-Insufficient duration or premature cessation of activity restrictions, leading to re-injury
-Failure to vaccinate post-splenectomy patients.