Overview

Definition:
-Supraventricular tachycardia (SVT) in children refers to a rapid heart rate originating above the ventricles, typically in the atria or AV node, with a heart rate exceeding 220 beats per minute in infants and 180 beats per minute in older children
-It is characterized by a narrow QRS complex on electrocardiogram (ECG) unless there is aberrant conduction
-Common types include AV nodal reentrant tachycardia (AVNRT), AV reentrant tachycardia (AVRT) utilizing an accessory pathway, and atrial tachycardia
-SVT is the most common symptomatic tachyarrhythmia in infants and children
-Clinical significance lies in its potential to cause hemodynamic instability, heart failure, and even cardiovascular collapse if prolonged or severe, necessitating prompt recognition and management.
Epidemiology:
-SVT accounts for approximately 5-10% of pediatric cardiac emergencies
-The incidence is estimated to be between 1 in 200 to 1 in 25,000 live births, with variations depending on the diagnostic criteria and population studied
-Neonates and infants are most commonly affected, with presentation often occurring within the first year of life
-Males are more commonly affected than females in infancy
-Recurrence is common, with up to 50% of infants experiencing a recurrence within the first year of diagnosis
-The presence of structural heart disease is uncommon in most pediatric SVT cases, with the majority being due to accessory pathways or nodal reentrant mechanisms.
Clinical Significance:
-Unrecognized or inadequately treated SVT can lead to significant morbidity in children
-Rapid heart rates reduce diastolic filling time, decreasing cardiac output and leading to symptoms such as irritability, poor feeding, pallor, sweating, tachypnea, and, in severe cases, hypotension, syncope, and cardiogenic shock
-In infants, this can present as "Infantile Tachycardia-Induced Cardiomyopathy." Prompt diagnosis and effective management are crucial to restore sinus rhythm, prevent complications, and improve long-term outcomes
-Understanding vagal maneuvers and pharmacologic interventions like adenosine is paramount for pediatricians and residents preparing for DNB and NEET SS examinations.

Clinical Presentation

Symptoms:
-In infants: Irritability
-Poor feeding
-Lethargy
-Pallor
-Vomiting
-Tachypnea
-Sweating
-In older children: Palpitations
-Chest pain
-Dizziness
-Lightheadedness
-Syncope
-Anxiety
-Shortness of breath.
Signs:
-Heart rate >180-220 bpm (depending on age)
-Narrow QRS complex (<0.08 sec) on ECG, unless bundle branch block or pre-excitation is present
-Regular rhythm
-May be difficult to palpate radial pulse
-Signs of poor perfusion: pallor, cool extremities, delayed capillary refill
-Signs of heart failure: hepatomegaly, rales, grunting respirations, increased work of breathing
-Possible cannon a waves in jugular venous pulse if atrial contraction is synchronous with ventricular contraction.
Diagnostic Criteria:
-Diagnosis is primarily based on ECG findings: Heart rate >180-220 bpm (infants) or >180 bpm (older children)
-Regular rhythm
-Narrow QRS complex
-P waves may be absent, retrograde, or conducted normally but difficult to discern
-Specific patterns on ECG may suggest the type of SVT (e.g., short RP’ interval in AVNRT, long RP’ interval in AVRT)
-Hemodynamic stability is a key determinant for management strategy.

Diagnostic Approach

History Taking:
-Detailed history of onset and duration of episodes
-Frequency of episodes
-Associated symptoms during episodes (irritability, feeding difficulties, syncope)
-Previous episodes or known cardiac history
-Family history of arrhythmias or sudden cardiac death
-Medications used
-Red flags: hemodynamic instability, signs of heart failure, associated congenital heart disease, syncope, family history of sudden death.
Physical Examination:
-Assess vital signs, including heart rate and blood pressure
-Observe for signs of distress and poor perfusion
-Auscultate heart for rate and rhythm
-Palpate peripheral pulses
-Assess for hepatomegaly and signs of heart failure
-A rapid, regular, narrow-complex tachycardia is the hallmark finding.
Investigations:
-12-lead ECG is essential for diagnosis and rhythm analysis
-It should be obtained during an episode if possible
-If ECG is unavailable during an episode, a continuous cardiac monitor or Holter monitor may be useful for subsequent evaluation
-Echocardiography may be indicated to assess for structural heart disease, particularly if the diagnosis is uncertain or if there are signs of heart failure
-Serum electrolytes and thyroid function tests are generally not useful in the acute management of SVT but may be considered in recurrent or refractory cases
-Advanced imaging like cardiac MRI is rarely needed for diagnosis of typical pediatric SVT.
Differential Diagnosis:
-Sinus tachycardia (usually variable rate, often related to fever, dehydration, pain, anxiety, or hyperthyroidism)
-Atrial flutter (sawtooth pattern of P waves)
-Atrial fibrillation (irregularly irregular rhythm)
-Ventricular tachycardia (wide QRS complex, usually slower rate, often associated with structural heart disease)
-Sinus node reentrant tachycardia
-Wandering atrial pacemaker
-Supraventricular extrasystoles
-Junctional ectopic tachycardia (JET), especially in post-operative cardiac patients (often wide QRS).

Management

Initial Management:
-Immediate assessment of hemodynamic stability
-If unstable (hypotension, altered mental status, signs of shock, acute heart failure, prolonged episode), immediate synchronized cardioversion (1-2 J/kg, increasing to 4 J/kg if needed) is the first-line treatment, irrespective of the rhythm
-If stable, attempt vagal maneuvers
-If unsuccessful or if the child is unable to tolerate them, pharmacologic therapy with adenosine is the next step.
Vagal Maneuvers:
-These aim to stimulate the vagus nerve to slow conduction through the AV node
-In infants and younger children: facial immersion in ice water (Valsalva maneuver with face mask)
-In older children: Valsalva maneuver (bearing down), carotid sinus massage (contraindicated in children with risk factors for carotid artery disease), or gagging
-Success rates vary, with higher success in conscious older children
-Perform with caution, especially carotid sinus massage.
Adenosine Pharmacology:
-Adenosine is a nucleoside that acts as a negative chronotrope and dromotrope by slowing conduction through the AV node and producing transient AV block
-It is the drug of choice for pharmacologic termination of most narrow-complex SVTs
-Pediatric dose: Rapid IV bolus of 0.1 mg/kg (max 6 mg), followed by a second bolus of 0.2 mg/kg (max 12 mg) if the first dose is ineffective
-Administer as a rapid bolus followed immediately by a 5-10 mL saline flush to minimize the short half-life and local effects
-Common side effects include transient flushing, dyspnea, chest discomfort, and a brief period of asystole or bradycardia, which are usually well-tolerated
-It is ineffective for SVTs originating above the AV node (e.g., atrial tachycardia).
Pharmacological Treatment Guidelines:
-If vagal maneuvers fail in a stable child, administer adenosine as described
-If adenosine is ineffective, consider other antiarrhythmic agents like procainamide (pediatric dose 2-5 mg/kg IV over 10-30 minutes, may repeat) or amiodarone (pediatric dose 5 mg/kg IV over 30-60 minutes)
-Verapamil is generally avoided in infants due to risk of profound hypotension and myocardial depression but may be considered cautiously in older children with documented AVNRT
-Long-term management may involve daily oral antiarrhythmic therapy (e.g., flecainide, sotalol, propranolol) or radiofrequency catheter ablation, especially for recurrent or difficult-to-manage SVT.
Supportive Care:
-Continuous cardiac monitoring is essential during and after treatment
-Observe for recurrence of SVT or development of other arrhythmias
-Monitor vital signs, including blood pressure and oxygen saturation
-Ensure adequate IV access
-Provide reassurance and comfort to the child and family.

Complications

Early Complications:
-Hypotension and shock from prolonged SVT or adverse drug reactions to adenosine (e.g., severe bradycardia, asystole)
-Paradoxical conversion to atrial fibrillation or flutter
-Myocardial dysfunction or heart failure due to prolonged tachycardia
-Injury from cardioversion (burns, arrhythmias).
Late Complications:
-Recurrent SVT episodes
-Development of atrial fibrillation in patients with accessory pathways
-Progressive left ventricular dysfunction (tachycardia-induced cardiomyopathy) if chronic or untreated SVT
-Developmental delays or neurological deficits if significant hypoxic events occurred
-Increased risk of syncope or falls in older children.
Prevention Strategies:
-Early identification and treatment of SVT episodes
-Maintaining sinus rhythm through optimal antiarrhythmic therapy or catheter ablation
-Education of parents/guardians on recognizing SVT and when to seek medical attention
-Regular follow-up with a pediatric cardiologist
-Avoiding triggers if known (e.g., dehydration, excessive stimulant intake in older children).

Prognosis

Factors Affecting Prognosis:
-Hemodynamic stability during episodes
-Presence or absence of structural heart disease
-Age at presentation (infants may have more severe initial presentation)
-Effectiveness of acute treatment and long-term management
-Frequency and duration of recurrent episodes.
Outcomes:
-The prognosis for most children with SVT is excellent, especially those with no underlying cardiac structural abnormalities and those who respond well to treatment
-The majority of episodes can be terminated with vagal maneuvers or adenosine
-Recurrence rates can be high, but many children outgrow SVT or can be effectively managed with medication or ablation
-Tachycardia-induced cardiomyopathy usually resolves with restoration and maintenance of sinus rhythm
-Long-term outcomes are generally favorable with appropriate medical follow-up.
Follow Up:
-Children with SVT should have regular follow-up with a pediatric cardiologist to monitor for recurrences, assess the effectiveness of therapy, and re-evaluate the need for long-term management
-This may include serial ECGs, Holter monitoring, and echocardiography as indicated
-Decision for electrophysiology study and catheter ablation is based on symptom burden, recurrence rates, and patient preference
-Education regarding recognition of symptoms and when to seek emergency care is crucial for families.

Key Points

Exam Focus:
-DNB/NEET SS will focus on differentiating SVT from sinus tachycardia and VT
-Know the pediatric doses of adenosine (0.1 mg/kg, then 0.2 mg/kg) and the importance of rapid IV push with saline flush
-Understand the indications for cardioversion versus pharmacologic therapy based on hemodynamic stability
-Recognize the ECG features of SVT
-Be aware of common causes of pediatric SVT (AVNRT, AVRT).
Clinical Pearls:
-Always assess hemodynamic stability first before attempting interventions
-Vagal maneuvers are safe and often effective, especially in older children
-Adenosine is the first-line drug for stable narrow-complex SVT, but it will not terminate atrial tachycardia
-If the child is refractory to adenosine, consider procainamide or amiodarone
-Be cautious with verapamil in infants
-Monitor for post-adenosine asystole as a benign but sometimes startling effect
-Recurrence is common, so patient education is key.
Common Mistakes:
-Confusing sinus tachycardia with SVT
-Delaying cardioversion in an unstable child
-Administering adenosine for atrial tachycardia
-Inadequate saline flush with adenosine, leading to prolonged side effects
-Using verapamil in infants without extreme caution
-Misinterpreting wide-complex tachycardias as SVT with aberrancy without considering VT
-Forgetting to reassess hemodynamic status after interventions.