Overview

Definition:
-Teething refers to the process of infant teeth erupting through the gums, often associated with discomfort and irritability
-Otitis media (OM) is an inflammation of the middle ear, typically caused by bacterial or viral infection, presenting with pain and potential systemic symptoms.
Epidemiology:
-Teething commonly occurs between 6-24 months of age, with peak incidence around 12-18 months
-Otitis media is the most common bacterial infection in young children, with a peak incidence between 6-18 months, often following a viral upper respiratory infection
-Up to 80% of children experience at least one episode of OM by age 3.
Clinical Significance:
-Accurate differentiation is crucial as teething is a benign physiological process managed with symptomatic relief, while otitis media requires medical evaluation and potential antibiotic treatment to prevent complications
-Misdiagnosis can lead to delayed treatment of infection or unnecessary interventions for a normal developmental stage.

Clinical Presentation

Symptoms:
-Teething: Increased drooling
-Chewing on objects
-Mild irritability or fussiness
-Sleep disturbances
-Low-grade fever (typically <38°C or 100.4°F)
-Refusal of food due to gum discomfort
-Mildly swollen or tender gums over erupting teeth
-Otitis Media: Moderate to high fever (often >38.5°C or 101.3°F)
-Ear pulling or tugging
-Increased crying and irritability, especially when lying down
-Difficulty sleeping
-Decreased appetite
-Possible clear or purulent nasal discharge
-Vomiting or diarrhea in some cases
-Hearing difficulties (intermittent).
Signs:
-Teething: Palpable raised areas on the gums corresponding to erupting teeth
-Redness or swelling of the gums
-Absence of other significant systemic symptoms or signs of infection
-Otitis Media: Tympanic membrane may appear red, bulging, opaque, and may have diminished mobility
-Fluid (effusion) may be visible behind the eardrum
-Decreased light reflex
-Possible tympanic membrane perforation with otorrhea.
Diagnostic Criteria:
-Diagnosis of teething is primarily clinical, based on age, history, and physical examination of the gums, in the absence of signs of infection
-Otitis media diagnosis typically relies on the presence of acute symptoms of middle ear inflammation plus middle ear effusion, as evidenced by tympanic membrane characteristics (bulging, limited mobility, fever, recent onset of otorrhea, or intense ear pain).

Diagnostic Approach

History Taking:
-Key history points: Age of the child
-Onset and duration of symptoms
-Fever (temperature, pattern)
-Presence of ear pulling/tugging
-Nasal congestion or discharge
-Cough
-Vomiting or diarrhea
-Feeding patterns
-Irritability level
-Any recent upper respiratory infection
-Red flags: High fever (>39°C), severe lethargy, difficulty breathing, stiff neck, dehydration, worsening ear pain despite initial treatment, discharge from the ear.
Physical Examination:
-Systematic examination approach: Assess general appearance and activity level
-Measure vital signs, including temperature
-Inspect the oropharynx for signs of infection (e.g., erythema, exudates)
-Carefully examine the ears using an otoscope, assessing the tympanic membrane characteristics (color, position, mobility, presence of fluid, perforation)
-Palpate cervical lymph nodes
-Auscultate lungs and heart.
Investigations:
-Investigations are usually not required for suspected teething
-For suspected otitis media, a diagnosis is primarily clinical
-However, in complex cases or if a different diagnosis is suspected, investigations might include: Rapid strep test or throat culture if pharyngitis is suspected
-Viral respiratory panel if significant respiratory symptoms are present
-Blood work (CBC) is rarely indicated but may show leukocytosis in bacterial infections
-Tympanometry can objectively assess middle ear pressure and eardrum compliance, useful in confirming effusion or assessing treatment response.
Differential Diagnosis:
-Conditions to consider: Teething is a diagnosis of exclusion
-Differential diagnoses for symptoms attributed to teething or OM include: Pharyngitis (viral or bacterial)
-Viral upper respiratory infections
-Tonsillitis
-Adenoiditis
-Cervical lymphadenitis
-Mastoiditis (a complication of OM, presenting with postauricular swelling and tenderness)
-External otitis (swimmer's ear)
-Dental abscess
-Meningitis (rare but critical to rule out with severe systemic symptoms).

Management

Initial Management:
-For suspected teething: Reassure parents that teething is normal
-Focus on symptomatic relief
-Advise on safe teething remedies
-For suspected otitis media: Assess severity and child's condition
-Initiate appropriate pain and fever management
-Consider antibiotics based on age, severity, and diagnostic certainty.
Medical Management:
-Teething: Offer chilled teethers or clean fingers for chewing
-Topical teething gels (e.g., containing benzocaine or lidocaine) should be used with caution and sparingly due to potential systemic absorption risks and toxicity, especially in young infants
-acetaminophen or ibuprofen may be considered for discomfort if needed
-Otitis Media: Pain relief: Acetaminophen (10-15 mg/kg/dose every 4-6 hours) or Ibuprofen (5-10 mg/kg/dose every 6-8 hours)
-Antibiotics: Amoxicillin (80-90 mg/kg/day divided every 12 hours) is the first-line treatment for uncomplicated acute otitis media in children over 6 months
-Alternative antibiotics include amoxicillin-clavulanate, cefdinir, cefuroxime, or azithromycin for specific indications or allergies
-Duration of treatment is typically 7-10 days for children < 2 years or with severe symptoms, and 5-7 days for children ≥ 2 years with mild-moderate symptoms.
Surgical Management:
-Surgical management is generally not indicated for simple teething or typical otitis media
-Myringotomy with tympanostomy tube insertion may be considered for recurrent acute otitis media (≥3 episodes in 6 months or ≥4 episodes in 12 months) or persistent otitis media with effusion for more than 3 months causing hearing loss or other complications.
Supportive Care:
-Teething: Offer fluids frequently
-Monitor for signs of dehydration
-Ensure safe sleep practices
-Otitis Media: Ensure adequate hydration
-Encourage rest
-Monitor for worsening symptoms or development of complications
-Follow-up with healthcare provider as recommended to assess treatment response.

Complications

Early Complications:
-Teething: Generally none, though discomfort can lead to poor feeding and sleep
-Otitis Media: Tympanic membrane perforation
-Otorrhea (discharge from the ear)
-Mastoiditis (infection of the mastoid bone)
-Facial nerve palsy
-Labyrinthitis
-Meningitis or intracranial abscess (rare)
-Sepsis.
Late Complications:
-Teething: None
-Otitis Media: Hearing loss (temporary due to effusion, or permanent due to scarring/cholesteatoma)
-Chronic suppurative otitis media
-Tympanosclerosis
-Cholesteatoma formation.
Prevention Strategies:
-Teething: None specific, it's a physiological process
-Otitis Media: Encourage breastfeeding
-Avoid exposure to tobacco smoke
-Promptly treat viral upper respiratory infections
-Vaccinations (pneumococcal, influenza)
-Consider prophylactic antibiotics in specific high-risk children, though this practice is less common now due to concerns of resistance.

Prognosis

Factors Affecting Prognosis:
-Teething: Excellent prognosis, symptoms resolve with tooth eruption
-Otitis Media: Generally good with appropriate treatment, especially for uncomplicated cases
-Factors influencing prognosis include age, severity of illness, presence of complications, and promptness of treatment
-Recurrence is common.
Outcomes:
-Teething: Resolution of symptoms once the tooth has fully erupted
-Otitis Media: Most children recover fully with resolution of infection and effusion
-Hearing typically returns to normal
-Recurrent episodes may occur
-Complicated OM or chronic effusion can lead to long-term sequelae.
Follow Up:
-Teething: No specific follow-up required unless complications arise
-Otitis Media: Follow-up within 24-48 hours if symptoms are severe or not improving
-A re-evaluation visit typically 4-6 weeks after completion of antibiotic therapy is recommended to confirm resolution of effusion and assess hearing, especially in children < 2 years or with persistent symptoms.

Key Points

Exam Focus:
-Differentiate low-grade fever/irritability of teething from moderate-high fever/ear pain of otitis media
-Recognize key otoscopic findings in OM (bulging, red TM)
-Understand first-line antibiotic choices and dosages for AOM
-Know indications for tympanostomy tubes
-Be aware of complications of untreated or recurrent OM.
Clinical Pearls:
-Always consider otitis media in an infant presenting with fever and fussiness
-A history of recent URI is a significant clue for OM
-Gentle tugging at the ear can indicate ear pain
-Tympanic membrane mobility assessment with pneumatic otoscopy is crucial for diagnosing effusion
-If in doubt, err on the side of caution and investigate OM, especially with fever.
Common Mistakes:
-Attributing all infant fussiness to teething without ruling out infection
-Underestimating the severity of otitis media
-Inappropriate antibiotic use (e.g., wrong dosage, duration, or indication)
-Not performing adequate follow-up to ensure resolution of OM and effusion.