Overview

Definition:
-Abdominal wall eventration, often referred to as a large ventral or incisional hernia, is characterized by the protrusion of abdominal contents through a defect in the abdominal wall musculature, where the fascial layers have been disrupted and do not approximate well, leading to a loss of abdominal domain
-Reconstruction aims to restore fascial integrity and abdominal wall function.
Epidemiology:
-Incisional hernias are a common complication of abdominal surgery, occurring in 5-20% of laparotomies
-Risk factors include wound infection, obesity, dehiscence, smoking, and poor nutritional status
-Eventration specifically refers to larger defects with loss of abdominal domain, posing greater reconstructive challenges.
Clinical Significance:
-Abdominal wall eventration significantly impacts patient quality of life due to pain, discomfort, and functional limitations
-More critically, it poses risks of incarceration and strangulation of abdominal contents, leading to bowel obstruction or ischemia
-Effective reconstruction is vital for symptom relief, preventing complications, and restoring abdominal wall mechanics.

Clinical Presentation

Symptoms:
-Visible bulge or swelling in the abdomen, often exacerbated by coughing, straining, or standing
-Pain or discomfort localized to the bulge
-Feeling of heaviness or pressure in the abdomen
-Difficulty with activities of daily living
-Nausea and vomiting if bowel obstruction is present.
Signs:
-A palpable defect in the abdominal wall, often with a reducible or irreducible bulge
-Skin changes over the hernia may include thinning, discoloration, or ulceration
-In cases of incarceration, the hernia contents may be tense and tender
-Signs of bowel obstruction may include distended abdomen, absent bowel sounds, and peritonitis.
Diagnostic Criteria:
-Diagnosis is primarily clinical, based on physical examination revealing a defect and contents protruding
-Imaging studies, such as CT scan, are used to assess the size and contents of the defect, evaluate for loss of domain, and identify associated intra-abdominal pathology
-No formal "diagnostic criteria" exist beyond clinical and radiological assessment.

Diagnostic Approach

History Taking:
-Detailed history of previous abdominal surgeries, including type of incision and any complications
-Onset and progression of the bulge
-Associated symptoms like pain, bowel changes, or respiratory distress
-Patient's comorbidities (obesity, COPD, diabetes) that may affect surgical outcome
-Smoking history.
Physical Examination:
-Thorough abdominal examination, including inspection for scars and bulges, palpation to define the defect size and contents, and assessment of reducibility
-Examine for signs of incarceration or strangulation
-Assess for ascites and evaluate respiratory function.
Investigations:
-Ultrasound can be useful for initial assessment
-CT scan of the abdomen and pelvis with intravenous contrast is the imaging modality of choice
-It helps delineate the fascial defect, quantify the hernia sac contents, assess for loss of abdominal domain (using techniques like the "loss of domain ratio"), and identify adhesions or other intra-abdominal pathology
-MRI may be used in select cases.
Differential Diagnosis: Other abdominal wall masses, lipomas, desmoid tumors, rectus sheath hematoma, seroma, abscess, endometrioma of the abdominal wall, and other types of hernias (e.g., spigelian hernia).

Management

Initial Management:
-For asymptomatic, reducible hernias without loss of domain, watchful waiting may be considered
-For symptomatic hernias, or those with risk of complications, surgical repair is indicated
-Urgent surgical intervention is required for incarcerated or strangulated hernias.
Surgical Management:
-Surgical repair aims to close the fascial defect and restore abdominal wall integrity
-Options include: 1
-Simple suture repair (rarely suitable for large defects)
-2
-Mesh repair (synthetic or biologic mesh) placed either anterior to the fascia (onlay), between fascial layers (inlay), or posterior to the peritoneum (underlay/sublay)
-3
-Component separation techniques (e.g., Rives-Stoppa, transversus abdominis release - TAR) which involve releasing the lateral abdominal muscles to achieve primary fascial closure, often combined with mesh
-4
-Robotic or laparoscopic approaches for less complex defects or component separation
-5
-Free flap reconstruction for very large or complex defects with tissue loss.
Preoperative Preparation:
-Optimizing patient health is crucial
-This includes smoking cessation, weight loss in obese patients, nutritional support (especially with low albumin), and glycemic control
-Antibiotic prophylaxis is standard
-Bowel preparation may be necessary for cases with bowel in the hernia sac
-Planning for appropriate surgical approach and mesh material.
Postoperative Care:
-Close monitoring for pain, infection, wound complications, and recurrence
-Early mobilization is encouraged
-Adequate analgesia
-Management of drains if placed
-Respiratory physiotherapy is important, especially after component separation
-Gradual return to activity
-Consider prophylactic anticoagulation in high-risk patients.
Supportive Care:
-Nutritional support is critical for wound healing
-Multidisciplinary team approach involving surgeons, anesthetists, dietitians, and physiotherapists
-Pain management strategies should be implemented proactively.

Complications

Early Complications: Wound infection, seroma, hematoma, mesh infection, mesh extrusion, skin necrosis, anastomotic leak (if bowel resection performed), ileus, pneumonia, urinary retention, deep vein thrombosis (DVT), pulmonary embolism (PE).
Late Complications: Hernia recurrence, chronic pain, meshoma, bowel obstruction due to adhesions, enterocutaneous fistula (rare), mesh migration, incisional hernia at a new site.
Prevention Strategies:
-Meticulous surgical technique, appropriate wound closure, use of prophylactic antibiotics, judicious use of mesh, patient optimization (weight loss, smoking cessation), good postoperative care including early mobilization and respiratory physiotherapy
-Careful selection of mesh type and placement technique is vital.

Prognosis

Factors Affecting Prognosis:
-Size of the defect, presence of loss of domain, patient comorbidities (obesity, diabetes, immunosuppression), history of wound infection, and surgeon's experience
-Recurrence rates vary significantly based on technique, with mesh repairs and component separation generally offering lower recurrence rates than simple suture repair for large defects.
Outcomes:
-Successful reconstruction leads to resolution of symptoms, improved quality of life, and reduced risk of complications
-Recurrence remains a significant concern, particularly for very large defects or in patients with multiple risk factors
-Long-term outcomes are generally good with modern reconstructive techniques, but require diligent follow-up.
Follow Up:
-Regular follow-up appointments are essential, typically at 1 week, 1 month, 6 months, and annually thereafter
-Follow-up focuses on assessing for signs of recurrence, wound complications, and patient satisfaction
-Imaging may be performed if recurrence is suspected clinically.

Key Points

Exam Focus:
-Understand the indications for different repair techniques (mesh vs
-component separation vs
-combined approaches)
-Be familiar with the principles of component separation (e.g., TAR) and their role in managing loss of domain
-Know the complications of mesh repair and strategies to minimize them
-Differentiate between large ventral hernias and simple incisional hernias.
Clinical Pearls:
-Always consider loss of domain in large ventral hernias, which dictates the need for component separation or staged repairs
-Preoperative optimization is paramount for successful outcomes
-Be aware of the potential for prosthetic infection and its devastating consequences
-Intraoperative assessment of the integrity of the fascial closure and mesh fixation is critical.
Common Mistakes:
-Attempting primary fascial closure for very large defects without considering component separation
-Inadequate preoperative optimization of the patient
-Poor selection of mesh material or inappropriate placement technique
-Insufficient postoperative care leading to complications
-Underestimating the risk of recurrence in complex cases.