Overview

Definition:
-Capsular contracture is the most common complication following breast augmentation or reconstruction with implants, characterized by the hardening and tightening of the fibrous capsule that naturally forms around the implant
-This process can lead to pain, distortion, and palpability of the implant.
Epidemiology:
-The incidence of capsular contracture varies widely, reported from 2% to over 30% depending on the implant type, surgical technique, and follow-up duration
-Factors such as implant surface texture, bacterial contamination, and patient susceptibility influence its occurrence.
Clinical Significance:
-Capsular contracture significantly impacts patient satisfaction and outcomes, often necessitating revision surgery
-Understanding its pathophysiology, risk factors, and management is crucial for all surgeons performing breast implant procedures, directly affecting patient care and aesthetic results.

Clinical Presentation

Symptoms:
-Breast hardness
-Discomfort or pain, often described as a dull ache or tightness
-Visible distortion or asymmetry of the breast mound
-Palpable implant edges or rippling
-Change in breast shape or position
-In severe cases, pain can be sharp and debilitating.
Signs:
-Increased firmness of the breast on palpation
-Restricted breast mobility
-Implants may be visibly displaced or distorted
-Rippling or wrinkling of the implant surface may be apparent, especially in thinner patients
-Palpable or visible scar tissue around the implant.
Diagnostic Criteria:
-The Baker Classification is commonly used to grade the severity of capsular contracture: Grade I (normal, no visible or palpable contracture)
-Grade II (breast is firm, implant slightly palpable, mild distortion)
-Grade III (breast is firm, implant easily palpable, noticeable distortion)
-Grade IV (breast is hard, immobile, implant deformed, pain present)
-Diagnosis is primarily clinical, supported by imaging if uncertainty exists.

Diagnostic Approach

History Taking:
-Detailed history of the initial surgery, including implant type, placement, and any previous complications
-Onset and progression of symptoms, particularly pain and breast hardness
-Previous treatments or interventions for contracture
-Patient's expectations and desire for revision surgery.
Physical Examination:
-Careful palpation of the breast tissue and implant to assess firmness, mobility, and detect any irregularities or pain
-Assess for symmetry, position, and any signs of implant rippling or extrusion
-Evaluate the overlying skin quality and any scarring
-Palpate axillary and supraclavicular lymph nodes.
Investigations:
-Ultrasound: Useful for assessing implant integrity, capsule thickness, and detecting fluid collections or implant displacement
-MRI: Highly sensitive for detecting subtle capsular contracture, implant rupture, and intracapsular fluid
-Mammography: Can be used but may be limited in visualization of implant-related changes
-specific techniques like Eklund views are recommended.
Differential Diagnosis:
-Implant rupture (intracapsular or extracapsular)
-Seroma or hematoma formation
-Infection
-Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL)
-Tumors of the breast
-Normal post-operative scarring.

Management

Initial Management:
-For mild cases (Baker Grade I/II), conservative management may involve observation and reassurance
-If acute inflammation or infection is suspected, prompt investigation and treatment are necessary
-Pain management with analgesics as needed.
Medical Management:
-Limited role for medical management alone
-However, leukotriene receptor antagonists (e.g., Montelukast) have been explored as adjunctive therapy in some cases to reduce inflammation and fibrosis, with mixed evidence
-Antibiotics are crucial if infection is present.
Surgical Management:
-Surgical intervention is the primary treatment for symptomatic capsular contracture (Baker Grade III/IV)
-Options include: Capsulectomy (excision of the fibrous capsule), implant removal and replacement (with or without new capsule formation), or revision of implant position
-Techniques aim to minimize trauma and bacterial contamination..
-Current recommendations favor smooth, round implants with a textured surface being largely phased out due to BIA-ALCL concerns.
Supportive Care:
-Post-operative care involves wound care, pain management, and close monitoring for signs of infection or hematoma
-Graduated compression garments may be used
-Long-term follow-up is essential to monitor for recurrence or new complications.

Complications

Early Complications:
-Hematoma
-Seroma
-Infection
-Wound dehiscence
-Capsular flap formation
-Implant malposition.
Late Complications:
-Recurrent capsular contracture
-Implant rupture
-Rippling
-Pain
-Altered sensation
-Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL).
Prevention Strategies:
-Meticulous surgical technique to minimize trauma and bacterial contamination
-Use of antibiotic irrigation and peri-operative antibiotic prophylaxis
-Optimal implant pocket creation
-Placement of smooth implants in a submuscular plane
-Avoiding drains where possible
-Careful patient selection
-Minimizing electrocautery use in the pocket
-Thorough irrigation of the pocket.

Prognosis

Factors Affecting Prognosis:
-Severity of initial contracture
-Choice of surgical technique and implant type
-Presence of infection or other complications
-Adherence to post-operative care
-Patient factors such as scar tissue formation tendency.
Outcomes:
-Successful treatment of capsular contracture can significantly improve patient comfort and aesthetic outcomes
-However, recurrence is possible, especially in severe cases or with less optimal surgical techniques
-Revision surgery offers a high chance of improvement but not always a complete resolution.
Follow Up:
-Regular clinical follow-up is recommended at intervals determined by the surgeon, typically 1 week, 1 month, 3 months, 6 months, and then annually
-Longer-term follow-up is crucial to monitor for late complications such as implant rupture or BIA-ALCL.

Key Points

Exam Focus:
-Understand the Baker classification system for grading capsular contracture
-Know the incidence, risk factors, and presentation of capsular contracture
-Recognize the surgical indications and options for management (capsulectomy, implant exchange)
-Differentiate capsular contracture from implant rupture and BIA-ALCL.
Clinical Pearls:
-Bilateral, symmetric, firm breasts without pain raise suspicion for Baker Grade II contracture
-Always consider the possibility of BIA-ALCL in patients with unilateral breast hardening and effusion
-Smooth implants are generally associated with lower rates of contracture than older textured implants, though BIA-ALCL risk is lower with textured implants.
Common Mistakes:
-Underestimating the importance of meticulous sterile technique during revision surgery
-Delaying surgical intervention for symptomatic contracture
-Inadequate capsulectomy, leaving behind significant scar tissue
-Failing to consider or investigate for BIA-ALCL in suspicious cases
-Poor patient selection for revision surgery.