Overview

Definition:
-Chest wall reconstruction is a surgical procedure aimed at restoring the structural integrity and function of the chest wall following extensive resections due to trauma, infection, tumors, or congenital deformities
-It often involves the use of prosthetic materials like synthetic mesh and metallic bars to provide rigidity and support.
Epidemiology:
-Incidence varies widely depending on the etiology
-large segment resections are most commonly necessitated by malignancies, followed by trauma and infection
-Congenital deformities like pectus excavatum/carinatum also represent a significant patient population requiring reconstruction, though often with different techniques.
Clinical Significance:
-Adequate chest wall reconstruction is crucial for protecting intrathoracic organs, facilitating effective ventilation, and preventing paradoxical motion
-Failure to achieve stable reconstruction can lead to severe respiratory compromise, chronic pain, and increased morbidity and mortality.

Indications

Resection For Malignancy: Primary chest wall tumors (sarcomas, chondrosarcomas, desmoid tumors) or metastatic disease requiring en bloc resection of involved ribs, sternum, or musculature.
Trauma: Severe flail chest with instability, large segmental defects resulting from blunt or penetrating trauma, or debridement of infected necrotic tissue.
Infection Or Osteomyelitis: Chronic osteomyelitis of the sternum or ribs, necrotizing infections (e.g., post-sternotomy mediastinitis), or fungal infections requiring extensive debridement.
Congenital Deformities:
-Severe pectus excavatum or carinatum cases where less invasive techniques are insufficient, or after failure of previous reconstructions
-Congenital absence of chest wall segments.
Revisional Surgery: Management of complications from previous chest wall surgeries, such as dehiscence, infection, or loss of structural integrity.

Preoperative Preparation

Detailed Imaging: CT scans with 3D reconstruction are essential for assessing the extent of defect, involvement of adjacent structures, and planning the size and shape of reconstructive materials.
Nutritional Assessment: Optimizing nutritional status, especially in patients undergoing extensive cancer surgery, to promote wound healing.
Pulmonary Evaluation:
-Assessment of respiratory function
-aggressive pulmonary toilet and physiotherapy are initiated preoperatively.
Blood Product Availability: Ensuring adequate availability of blood products due to potential for significant intraoperative bleeding.
Multidisciplinary Team Discussion: Involving thoracic surgeons, oncologists, plastic surgeons, intensivists, and anesthesiologists for complex cases.

Surgical Management

Mesh Selection And Placement:
-Non-absorbable synthetic mesh (e.g., polypropylene, Marlex, Gore-Tex) is commonly used to provide a rigid framework
-It is typically sutured to the remaining intact bone or soft tissues, creating a stable scaffold.
Bar Fixation Techniques:
-Metallic bars (e.g., stainless steel, titanium) or specialized plating systems are used to reinforce the mesh, particularly in cases of significant sternal or rib defects
-They are anchored to stable bone structures proximal to the defect.
Sternal Reconstruction: For sternal defects, a composite reconstruction with mesh and potentially strut bars may be employed, often combined with autologous grafts or flaps for soft tissue coverage.
Rib Reconstruction: Individual ribs may be reconstructed using mesh or pre-contoured plates and bars, depending on the segmental loss and required stability.
Soft Tissue Coverage: Coverage of the reconstructed chest wall with vascularized flaps (e.g., latissimus dorsi, pectoralis major) or skin grafts is crucial to prevent infection and promote healing.

Postoperative Care

Intensive Monitoring: Close monitoring in an ICU setting is mandatory to assess respiratory status, hemodynamics, and pain control.
Mechanical Ventilation: Patients may require prolonged mechanical ventilation postoperatively to ensure adequate oxygenation and ventilation, especially after extensive reconstructions.
Pain Management: Aggressive pain management using multimodal approaches, including epidural analgesia, patient-controlled analgesia (PCA), and judicious use of opioids.
Chest Tube Management: Chest tubes are typically placed for pleural drainage and are monitored closely for output and air leaks.
Mobilization And Physiotherapy: Early mobilization and aggressive pulmonary physiotherapy are vital to prevent atelectasis, pneumonia, and venous thromboembolism.

Complications

Early Complications:
-Wound infection
-Mesh dehiscence or extrusion
-Pneumonia
-Acute respiratory failure
-Hemorrhage
-Pleural effusion or empyema.
Late Complications:
-Chronic pain
-Persistent paradoxical motion
-Mesh-related complications (e.g., seroma, late infection)
-Impaired respiratory function
-Psychological distress.
Prevention Strategies:
-Meticulous surgical technique with adequate debridement and sterile handling of mesh
-Aggressive wound care and early institution of antibiotics
-Optimal pain control and early mobilization
-Use of antibiotic-eluting mesh or beads
-Ensuring adequate soft tissue coverage.

Key Points

Exam Focus:
-Understand the indications for mesh and bar reconstruction
-Differentiate between various prosthetic materials and their applications
-Recognize common complications and their management
-Be familiar with reconstructive techniques for sternal and rib defects.
Clinical Pearls:
-Pre-operative CT with 3D reconstruction is indispensable for planning
-Adequate soft tissue coverage is paramount to prevent infection and dehiscence
-Multidisciplinary approach is key for complex cases.
Common Mistakes:
-Inadequate assessment of defect size leading to insufficient material
-Poor fixation of bars or mesh
-Insufficient soft tissue coverage
-Underestimating the need for prolonged mechanical ventilation and aggressive physiotherapy.