Overview

Definition:
-Damage control laparotomy (DCL) is a staged surgical approach used in severely injured patients with intra-abdominal hemorrhage or contamination, involving rapid control of bleeding and contamination, temporary closure of the abdomen, and planned re-exploration
-Temporary abdominal closure (TAC) techniques aim to facilitate fluid management, prevent evisceration, and prepare for definitive repair in a less compromised patient.
Epidemiology:
-DCL is employed in approximately 5-10% of abdominal trauma cases requiring laparotomy
-The incidence is higher in penetrating trauma, particularly gunshot wounds to the abdomen, and in patients with significant coagulopathy and hypothermia (the "lethal triad").
Clinical Significance:
-DCL and TAC are life-saving strategies for patients with severe abdominal trauma or intra-abdominal sepsis who are hemodynamically unstable and cannot tolerate prolonged definitive surgery
-They allow for resuscitation and correction of physiological derangements before attempting definitive repair, significantly improving survival rates.

Indications

Indications For Dcl:
-Hemodynamic instability (hypotension with acidosis and coagulopathy) despite aggressive fluid resuscitation and blood transfusion
-Presence of intra-abdominal hemorrhage, widespread contamination (e.g., hollow viscus perforation, mesenteric devascularization), or suspected occult injury
-Inability to achieve adequate hemostasis or control contamination within a reasonable timeframe during initial laparotomy.
Indications For Tac:
-Following DCL, abdominal compartment syndrome, or situations where definitive closure would compromise organ perfusion or respiratory function
-Severe edema of bowel loops preventing closure
-Patients with anticipated need for further intra-abdominal interventions (e.g., repeat laparotomy for sepsis, re-exploration for bleeding).
Contraindications To Dcl:
-Stable hemodynamics
-Limited intra-abdominal pathology
-Clear operative field without significant bleeding or contamination
-Patients for whom definitive repair can be safely accomplished in a single setting.

Diagnostic Approach

Initial Assessment:
-Rapid primary survey according to ATLS protocols
-Assessment of ABCs (Airway, Breathing, Circulation)
-Identification of shock and coagulopathy
-History from EMS or patient if available, focusing on mechanism of injury and time elapsed.
Imaging:
-FAST (Focused Assessment with Sonography for Trauma) examination for free fluid
-CT scan of the abdomen and pelvis in stable patients to identify solid organ injury, bowel perforation, and vascular injury
-Diagnostic peritoneal lavage (DPL) may be used in hemodynamically unstable patients where FAST is equivocal.
Laboratory Investigations:
-Complete blood count (CBC) for hemoglobin and platelet count
-Coagulation profile (PT, INR, aPTT)
-Blood gas analysis for acidosis
-Serum lactate for tissue hypoperfusion
-Cross-matching for blood products.

Management

Surgical Management Dcl:
-Initial laparotomy is performed to rapidly identify and control sources of bleeding and gross contamination
-Packing of the abdomen is used to control oozing
-Resuscitation with blood products, crystalloids, and colloids is continued
-Correction of coagulopathy and hypothermia is paramount
-The abdomen is then temporarily closed using various TAC techniques, avoiding tension on the abdominal wall.
Temporary Abdominal Closure Techniques:
-Bogota bag technique (using a sterile drainage bag sutured to the fascial edges)
-Mesh repair (using synthetic or biological mesh, which may be sutured or secured with clips)
-Zipper closure systems
-Vacuum-assisted closure (VAC) systems, often applied over a barrier like a plastic sheet or mesh
-Simplest methods include approximation of fascial edges with sutures or clamps, if feasible.
Resuscitation And Optimization:
-Aggressive fluid and blood resuscitation
-Correction of coagulopathy with fresh frozen plasma, cryoprecipitate, and platelet transfusions
-Administration of warming blankets and warmed intravenous fluids to combat hypothermia
-Management of acidosis with bicarbonate if severe.
Definitive Repair And Reoperation:
-Planned re-exploration within 24-72 hours, once the patient is physiologically stable and coagulopathy is corrected
-During re-exploration, the abdomen is opened, irrigated, and definitive repairs are performed, including resection and anastomosis of bowel, vascular repair, and solid organ management
-The abdomen is then closed definitively if possible, or TAC may be reapplied if indicated.

Complications

Early Complications:
-Abdominal compartment syndrome due to inadequate decompression or excessive fluid resuscitation
-Postoperative bleeding
-Sepsis from retained contamination or anastomotic leak
-Enterocutaneous fistula formation
-Ventilator-associated pneumonia
-Deep vein thrombosis and pulmonary embolism.
Late Complications:
-Incisional hernia formation, especially after mesh use or multiple reoperations
-Adhesions and bowel obstruction
-Chronic pain
-Psychological sequelae.
Prevention Strategies:
-Judicious use of fluid resuscitation
-Prompt correction of coagulopathy
-Aggressive management of hypothermia and acidosis
-Early recognition and management of abdominal compartment syndrome
-Meticulous surgical technique during definitive repair
-Use of prophylactic antibiotics
-Early mobilization and DVT prophylaxis.

Prognosis

Factors Affecting Prognosis:
-Severity of injury (ISS score)
-Degree of initial shock and coagulopathy
-Presence of multiple comorbidities
-Promptness and adequacy of resuscitation and DCL/TAC
-Occurrence of intra-abdominal sepsis or organ failure
-Time to definitive repair.
Outcomes:
-Mortality rates for DCL vary significantly, ranging from 20% to over 50%, depending on the severity of the initial injury and patient condition
-Survival has improved with the widespread adoption of DCL and TAC principles
-Patients undergoing DCL often have prolonged hospital stays and higher rates of morbidity.
Follow Up:
-Close monitoring for signs of infection, bleeding, or organ dysfunction
-Regular assessment of abdominal girth and urine output
-Management of nutritional support
-Plans for hernia repair if indicated, typically after 6-12 months post-injury or definitive closure.

Key Points

Exam Focus:
-Understand the "lethal triad" (hypothermia, coagulopathy, acidosis) and its management
-Know the indications for DCL and TAC
-Recognize different TAC techniques and their advantages/disadvantages
-Recall the staged nature of DCL: control, temporary closure, resuscitation, re-exploration, definitive repair.
Clinical Pearls:
-Do not be afraid to temporize! The goal of DCL is to buy time for resuscitation
-Aggressively manage coagulopathy
-even minor improvements can be life-saving
-Use warming measures proactively
-Document all findings meticulously in the abdomen during initial laparotomy, as re-exploration may be challenging.
Common Mistakes:
-Attempting definitive repair in a hemodynamically unstable patient
-Inadequate resuscitation and correction of derangements before re-exploration
-Over-reliance on a single TAC technique without considering patient-specific factors
-Premature definitive abdominal closure in edematous bowel
-Failure to plan for timely re-exploration.