Overview

Definition:
-Decortication is a surgical procedure to remove a thick, inelastic peel or membrane (false membrane or peel) that has formed over the lung surface, typically as a consequence of chronic inflammation, infection, or trauma
-This peel restricts lung expansion and can lead to respiratory compromise
-Thoracotomy is the surgical approach used to access the pleural space and perform the decortication.
Epidemiology:
-The incidence of conditions requiring decortication, such as chronic empyema and fibrothorax, is influenced by factors like the prevalence of pneumonia, tuberculosis, and surgical site infections
-It is a relatively uncommon but significant complication of pleural diseases, affecting all age groups but particularly those with compromised immune systems or pre-existing lung conditions.
Clinical Significance:
-Decortication is crucial for restoring lung function in patients with restrictive lung disease due to pleural encasement
-Failure to address this can lead to chronic dyspnea, recurrent infections, pulmonary hypertension, and reduced quality of life
-For surgical residents, understanding the indications, techniques, and complications is vital for managing complex thoracic pathologies.

Indications

For Decortication:
-Chronic empyema that has failed to resolve with antibiotics and chest tube drainage
-Fibrothorax where a thick peel restricts lung expansion
-Trapped lung after pleurodesis or pneumonectomy
-Organizer pneumonia
-Malignant pleural effusions with significant pleural thickening and entrapment
-Cases of loculated effusions resistant to simple aspiration.
For Thoracotomy Approach:
-Thoracotomy provides direct visualization and adequate space for aggressive lysis of adhesions and removal of thick peel
-It is often necessary for complete decortication, especially when the peel is dense or extensive
-Minimally invasive approaches may be considered for less complex cases, but thoracotomy remains the gold standard for extensive decortication.
Contraindications:
-Severe coagulopathy
-Uncontrolled sepsis
-Moribund patients with irreversible respiratory failure
-Inability to tolerate a major surgical procedure due to comorbidities
-Active pneumonia in the ipsilateral lung
-Extensive pulmonary parenchymal disease that would preclude functional recovery.

Preoperative Preparation

History And Examination:
-Thorough history focusing on duration of symptoms, previous infections, and prior thoracic interventions
-Physical examination to assess respiratory status, evidence of effusion, and chest wall abnormalities.
Imaging:
-Chest X-ray for initial assessment of pleural space
-Contrast-enhanced CT scan of the thorax is essential to delineate the extent of the peel, assess lung involvement, identify loculations, and evaluate the mediastinal and hilar lymph nodes
-Ultrasound may be used to guide diagnostic thoracentesis.
Pulmonary Function Tests:
-PFTs are crucial to assess baseline lung function and predict postoperative recovery
-Parameters like FEV1, FVC, and DLCO are important
-Arterial blood gas analysis provides information on oxygenation and ventilation.
Optimization:
-Antibiotic therapy for active infection
-Nutritional support and physiotherapy to optimize respiratory muscle strength
-Bronchodilators if underlying airway disease is present
-Correction of coagulopathy and electrolyte imbalances
-Smoking cessation counseling.

Procedure Steps

Anesthesia And Positioning:
-General anesthesia with double-lumen endotracheal tube for single-lung ventilation
-Lateral decubitus position with the affected side uppermost.
Thoracotomy Incision: Posterolateral or anterolateral thoracotomy incision, typically in the 4th or 5th intercostal space, depending on the extent of disease.
Pleural Exploration:
-Upon entering the pleural space, the extent and thickness of the peel are assessed
-Any purulent material or organized debris is evacuated.
Decortication Technique:
-The peel is meticulously dissected from the visceral pleura and lung surface
-Dissection begins at the hilum and proceeds peripherally
-Care is taken to avoid injury to the lung parenchyma, intercostal vessels, and nerves
-Cavities or loculations are opened and debrided.
Lung Reinflation:
-Once decortication is complete, the lung is fully inflated to ensure it expands adequately and that there are no air leaks
-Chest drains (usually two) are inserted, one in the apical and one in the basal position, to drain air and fluid.
Chest Closure:
-Intercostal muscles and subcutaneous tissues are approximated, and the skin is closed in layers
-Intercostal drains are connected to an underwater seal drainage system.

Postoperative Care

Pain Management:
-Aggressive pain control is essential using epidural analgesia, patient-controlled analgesia (PCA) with opioids, or intercostal nerve blocks
-This facilitates deep breathing and early mobilization.
Respiratory Support:
-Early mobilization, incentive spirometry, and chest physiotherapy are vital to prevent atelectasis and pneumonia
-Humidified oxygen therapy as needed
-Monitoring of oxygen saturation and arterial blood gases.
Drain Management:
-Chest drains are monitored for drainage volume, character, and air leak
-Drains are typically removed when drainage is minimal (<100-150 ml/24h) and there is no air leak.
Antibiotics:
-Continue appropriate antibiotics if an infectious process was the cause of the empyema or if there is a concern for postoperative infection
-Prophylactic antibiotics may be considered in select cases.
Mobilization: Early ambulation is encouraged to promote lung expansion, venous return, and prevent deep vein thrombosis and pulmonary embolism.

Complications

Early Complications:
-Bleeding requiring re-operation
-Persistent air leak leading to prolonged drainage and potential need for re-operation
-Respiratory failure and pneumonia
-Bronchopleural fistula
-Injury to phrenic nerve or recurrent laryngeal nerve.
Late Complications:
-Chronic pain syndrome
-Empyema recurrence
-Residual pleural thickening and restrictive lung disease
-Adhesions leading to reduced lung function
-Scars and cosmetic deformities.
Prevention Strategies:
-Meticulous surgical technique to minimize trauma and bleeding
-Adequate chest drainage and early removal once appropriate
-Aggressive pain management to facilitate deep breathing
-Early mobilization and physiotherapy
-Prompt recognition and management of postoperative complications
-Judicious use of intraoperative antibiotics.

Prognosis

Factors Affecting Prognosis:
-The underlying etiology (e.g., chronic empyema vs
-malignancy)
-The duration and severity of the pleural disease
-The degree of lung entrapment and the extent of decortication
-Preoperative pulmonary function
-Patient's overall health and comorbidities
-Presence of postoperative complications.
Outcomes:
-Successful decortication can lead to significant improvement in lung function and resolution of dyspnea, especially in cases of chronic empyema or fibrothorax
-Patients with underlying malignant disease have a poorer prognosis related to the cancer itself
-Long-term survival depends on the underlying pathology and the success of the procedure in restoring lung mechanics.
Follow Up:
-Regular follow-up with chest X-rays and pulmonary function tests is recommended
-Patients should be monitored for signs of recurrence, infection, or persistent restrictive physiology
-Education on breathing exercises and lifestyle modifications is important.

Key Points

Exam Focus:
-Understand the definition and indications for decortication
-Differentiate between uncomplicated pleural effusion and complicated empyema requiring decortication
-Recognize the role of CT scan in preoperative assessment
-Be familiar with the standard thoracotomy approach and the steps of decortication
-Key complications include bleeding, air leak, and recurrent empyema.
Clinical Pearls:
-The goal is to achieve a fully expanded lung with a functional pleural space
-Meticulous dissection is key to avoid lung injury
-Adequate chest tube placement and management are critical for success
-Pain control is paramount for postoperative recovery
-Early mobilization is a cornerstone of care.
Common Mistakes:
-Inadequate preoperative assessment leading to unexpected findings or technical difficulties
-Insufficient debridement of the peel, leading to incomplete lung expansion
-Aggressive dissection causing parenchymal injury or bleeding
-Poor pain control resulting in shallow breathing and atelectasis
-Delayed recognition of complications like persistent air leak or bronchopleural fistula.