Overview

Definition:
-Dor fundoplication is a surgical procedure performed to correct gastroesophageal reflux disease (GERD) by creating an anterior partial wrap of the gastric fundus around the distal esophagus
-It is a type of partial fundoplication, aiming to restore the function of the lower esophageal sphincter (LES) to prevent the retrograde flow of gastric contents into the esophagus.
Epidemiology:
-GERD affects approximately 20% of the adult population in Western countries, with a significant proportion experiencing refractory symptoms despite medical management
-Surgical intervention is considered for patients with persistent symptoms, complications of GERD, or those preferring definitive treatment
-Dor fundoplication is one of the surgical options employed.
Clinical Significance:
-For surgical residents and DNB/NEET SS candidates, understanding Dor fundoplication is crucial as it represents a common and effective treatment for severe GERD
-Proficiency in its indications, surgical technique, potential complications, and patient selection is vital for comprehensive surgical knowledge and successful examination performance
-It directly impacts patient care by offering a durable solution for a prevalent condition.

Indications

Symptomatic Gerd: Patients with persistent heartburn, regurgitation, or other GERD symptoms that are refractory to optimal medical management (e.g., PPI therapy).
Demonstrated Esophagitis: Objective evidence of GERD, such as positive 24-hour pH monitoring or esophageal manometry, and significant esophageal damage (e.g., erosive esophagitis, Barrett's esophagus).
Hiatal Hernia: Often performed in conjunction with the repair of a paraesophageal or sliding hiatal hernia, where the hiatal hernia contributes to GERD.
Patient Preference: Patients who desire definitive surgical treatment to avoid long-term medication or who have contraindications or intolerance to medical therapy.
Refractory Dysphagia: In select cases, carefully chosen patients with reflux-induced dysphagia may benefit from surgery, although this is a relative indication.

Preoperative Preparation

Diagnostic Evaluation:
-Comprehensive evaluation including upper endoscopy to assess the severity of esophagitis, rule out Barrett's esophagus or malignancy
-24-hour esophageal pH monitoring and manometry to confirm GERD and assess LES function.
Medical Optimization: Patients are typically placed on high-dose proton pump inhibitors (PPIs) for 4-8 weeks preoperatively to suppress acid production and allow for healing of esophageal mucosa.
Nutritional Assessment: Evaluation of nutritional status, especially if significant weight loss or malnutrition is present due to GERD symptoms.
Patient Counseling: Detailed discussion with the patient about the risks, benefits, alternatives, and expected outcomes of Dor fundoplication, including potential for postoperative gas bloat, dysphagia, and early satiety.
Anesthesia Considerations: Pre-anesthetic assessment to identify any comorbidities that may affect anesthetic management.

Procedure Steps

Trocar Placement: Laparoscopic approach involves placement of multiple trocars in the upper abdomen for instrument insertion, typically using 4-5 ports.
Hiatal Dissection:
-Mobilization of the gastric fundus and short gastric vessels
-Careful dissection of the crura of the diaphragm to identify and reduce any hiatal hernia.
Esophageal Mobilization:
-Creation of a window posterior to the esophagus to allow for passage of the gastric wrap
-Avoid excessive esophageal mobilization to prevent injury to the vagal nerves.
Fundoplication Wrap:
-The gastric fundus is brought anteriorly and partially wrapped (approximately 180-200 degrees) around the intra-abdominal esophagus, secured with sutures
-The wrap should be loose enough to prevent severe dysphagia but tight enough to provide an effective seal.
Mesh Repair: If a hiatal hernia is present, the crura are approximated with sutures to narrow the diaphragmatic hiatus, often reinforced with a synthetic or biological mesh, particularly in recurrent cases or large hernias.

Postoperative Care

Pain Management:
-Adequate analgesia, typically with intravenous or oral opioids, transitioning to NSAIDs as tolerated
-Multimodal pain management is encouraged.
Dietary Progression:
-Patients are usually started on a clear liquid diet and advanced to a full liquid, then pureed, soft, and eventually regular diet as tolerated, over several days to weeks
-Avoid carbonated beverages and gas-producing foods initially.
Early Ambulation: Encourage early mobilization to reduce the risk of venous thromboembolism and improve pulmonary function.
Monitoring For Complications:
-Close observation for signs of bleeding, infection, anastomotic leak, or other surgical complications
-Vital signs and urine output are monitored closely.
Discharge Criteria:
-Discharge planning includes pain control, ability to tolerate diet, ambulation, and absence of significant surgical complications
-Patients are advised to avoid heavy lifting for 4-6 weeks.

Complications

Early Complications:
-Bleeding from surgical sites
-Injury to adjacent organs (spleen, stomach, esophagus)
-Pneumothorax from diaphragmatic dissection
-Postoperative nausea and vomiting
-Wound infection
-Retrosternal pain.
Late Complications:
-Dysphagia (difficulty swallowing) is common and can be transient or persistent, requiring dilatation
-Gas bloat syndrome (abdominal distension and pain due to inability to belch)
-Persistent reflux symptoms if the wrap is inadequate
-Diarrhea
-Gastric outlet obstruction
-Suture dehiscence of the wrap or hiatal repair.
Prevention Strategies:
-Meticulous surgical technique, especially during esophageal and diaphragmatic dissection
-Proper sizing and tensioning of the fundic wrap
-Careful patient selection and preoperative counseling
-Gradual dietary advancement postoperatively
-Judicious use of mesh for hiatal repair.

Prognosis

Factors Affecting Prognosis:
-Success is generally high for selected patients, with symptom relief reported in 80-90%
-Factors influencing outcome include accuracy of diagnosis, surgical technique, surgeon experience, and patient adherence to postoperative dietary recommendations.
Outcomes:
-Most patients experience significant relief of heartburn and regurgitation
-Long-term dependence on PPIs is often reduced or eliminated
-However, some patients may still require occasional PPIs or experience recurrent symptoms.
Follow Up:
-Regular follow-up is typically scheduled at 1 week, 1 month, 3 months, and 6 months postoperatively, with further follow-up as needed
-This allows for monitoring of symptoms, dietary tolerance, and identification of any late complications
-Long-term follow-up is important for patients with Barrett's esophagus or other premalignant conditions.

Key Points

Exam Focus:
-Dor fundoplication is an anterior partial wrap (180-200 degrees)
-Indications include refractory GERD, esophagitis, and hiatal hernia repair
-Complications like dysphagia and gas bloat are common
-Differentiate from Nissen (360 degrees posterior) and Toupet (270 degrees posterior) fundoplications.
Clinical Pearls:
-Adequate esophageal mobilization while preserving vagal nerves is key
-Avoid overly tight wraps to minimize dysphagia
-Gradual dietary progression is crucial for patient recovery and symptom management
-Consider manometry preoperatively to assess esophageal motility disorders which may contraindicate certain wraps.
Common Mistakes:
-Inadequate patient selection (e.g., operating on patients with motility disorders or without objective evidence of GERD)
-Excessive esophageal mobilization or vagal nerve injury
-Creation of a too-tight or too-loose wrap
-Failure to address hiatal hernia appropriately
-Inadequate postoperative dietary guidance.