Overview

Definition:
-Endovascular Aneurysm Repair (EVAR) is a minimally invasive surgical procedure used to treat aneurysms, particularly abdominal aortic aneurysms (AAA) and thoracic aortic aneurysms (TAA)
-It involves deploying a stent graft within the aneurysm sac, which reinforces the aorta and prevents blood from flowing into the weakened wall of the aneurysm, thereby reducing the risk of rupture.
Epidemiology:
-Aneurysms, especially AAAs, are more common in older individuals (over 65 years), men, smokers, and those with a family history
-The prevalence of AAA in the general population is estimated to be between 4-8%, with higher rates in specific demographic groups
-EVAR has become the preferred treatment for a significant proportion of eligible AAA patients in developed countries.
Clinical Significance:
-Aneurysm rupture is a catastrophic event with high mortality rates
-EVAR offers a less invasive alternative to open surgical repair, leading to shorter recovery times, reduced morbidity, and mortality for carefully selected patients
-Understanding EVAR is crucial for vascular surgeons, general surgeons, and interventional radiologists involved in the management of aortic diseases.

Indications

General Indications:
-Symptomatic aneurysms require urgent intervention
-Asymptomatic aneurysms are typically repaired when they reach a certain diameter (e.g., >5.5 cm for AAA in men, >5.0 cm in women) or demonstrate rapid expansion (>0.5 cm in 6 months)
-Risk of rupture must outweigh the risks of the procedure.
Anatomical Suitability:
-The aneurysm must be amenable to EVAR based on imaging
-Key factors include the presence of adequate sealing zones (proximal and distal to the aneurysm), the absence of unfavorable angulation, tortuosity, or excessive thrombus that could compromise stent graft deployment and sealing.
Patient Factors:
-Patient comorbidities and life expectancy are considered
-EVAR is often favored in patients who are poor candidates for open surgery due to advanced age or significant comorbidities such as cardiac, pulmonary, or renal insufficiency.

Preoperative Preparation

Imaging Assessment:
-Multidetector-row computed tomography angiography (MDCT) is essential to precisely map the aneurysm, including neck length, diameter, angulation, iliac artery anatomy, and presence of thrombus
-Preoperative planning software is often used.
Risk Stratification:
-Comprehensive assessment of cardiovascular, pulmonary, renal, and cerebrovascular status
-Anesthesia risks are evaluated
-Patients undergo thorough medical workup.
Informed Consent: Detailed discussion with the patient and family about the procedure, benefits, risks (including endoleak, graft migration, rupture, stroke, renal failure, access site complications), alternatives to EVAR, and the need for lifelong surveillance.
Anticoagulation Strategy:
-Appropriate preoperative anticoagulation or antiplatelet therapy is determined based on patient factors and institutional protocols
-Prophylactic antibiotics are administered.

Procedure Steps

Access And Sheath Placement:
-Bilateral femoral arteries are accessed, typically via open arteriotomy or percutaneous techniques
-Large-bore sheaths are introduced to facilitate stent graft delivery.
Stent Graft Delivery And Deployment:
-The stent graft, a fabric-covered stent, is advanced through the sheaths to the target location within the aorta
-It is then deployed, expanding to seal against the aortic wall above and below the aneurysm.
Completion Angiography And Assessment:
-Post-deployment angiography confirms proper placement, seal, and absence of significant endoleaks
-Intraoperative imaging (fluoroscopy) is critical throughout the procedure
-Additional sealing techniques or limb extensions may be used if necessary.
Closure: Femoral access sites are closed using sutures, vascular staples, or closure devices.

Postoperative Care

Immediate Monitoring:
-Close monitoring of vital signs, urine output, and access site for bleeding or hematoma
-Pain management and fluid resuscitation are initiated
-Serial Doppler ultrasound may be used to assess graft patency.
Imaging Surveillance:
-Early postoperative imaging (CT scan or ultrasound) is performed within 30 days to assess graft integrity, sealing, and detect endoleaks
-Ongoing surveillance typically involves CT angiography or ultrasound at 6 months, 1 year, and then annually, or as indicated by findings.
Management Of Complications:
-Prompt recognition and management of endoleaks (Type I, II, III, IV, V)
-Management options for endoleaks include endovascular re-intervention, open surgical conversion, or conservative management depending on the type and clinical significance.
Lifestyle Modifications: Smoking cessation, blood pressure control, and management of hyperlipidemia are strongly encouraged to reduce further cardiovascular risk and prevent graft complications.

Complications

Early Complications:
-Access site complications (hematoma, pseudoaneurysm, infection)
-Endoleak (most common immediate complication)
-Stroke
-Myocardial infarction
-Renal dysfunction
-Graft limb occlusion
-Hypotension.
Late Complications:
-Graft migration
-Stent fracture
-Endoleak (persistent or new onset)
-Graft infection
-Aortic rupture (rare, but possible if endoleak is untreated)
-Endograft-enteric or endograft-venous fistula
-Juxtarenal or infrarenal neck dilation.
Prevention Strategies:
-Meticulous patient selection based on anatomical suitability
-Precise preoperative planning
-Experienced procedural team
-Use of appropriate stent graft technology
-Aggressive management of endoleaks
-Lifelong surveillance to detect and treat complications early.

Key Points

Exam Focus:
-EVAR is a minimally invasive technique for AAA/TAA repair
-Key anatomical requirements are adequate proximal and distal sealing zones
-Endoleaks are the most common complication
-understanding their types and management is critical.
Clinical Pearls:
-Never underestimate the importance of lifelong surveillance after EVAR
-A small type II endoleak from a lumbar artery may be monitored if asymptomatic and the sealing zones are intact
-Consider hybrid approaches for complex anatomies.
Common Mistakes:
-Inadequate preoperative imaging leading to poor anatomical assessment
-Failure to identify all potential sources of endoleak
-Over-reliance on percutaneous access in unsuitable patients
-Insufficient postoperative surveillance leading to delayed diagnosis of complications.