Overview

Definition:
-Fistulotomy is a surgical procedure used to treat anal fistulas by opening the fistula tract and allowing it to heal as a superficial wound
-It is primarily indicated for low anal fistulas, typically those originating from the Goodsall's rule, where the internal opening is located in the posterior midline and the external opening is within 3 cm of the anal verge.
Epidemiology:
-Anal fistulas affect approximately 1-3% of the population, with men being more commonly affected than women
-Low anal fistulas (transsphincteric and intersphincteric, less than 30% of the external anal sphincter) constitute a significant proportion of these cases
-They are often secondary to an anal gland infection or abscess.
Clinical Significance:
-Untreated anal fistulas can lead to chronic pain, recurrent abscesses, incontinence, and social embarrassment
-Fistulotomy offers a definitive solution for low anal fistulas with a high success rate, preserving anal sphincter function when performed correctly, which is crucial for patient quality of life and surgical resident training.

Clinical Presentation

Symptoms:
-Persistent purulent or fecal discharge from an opening in the perianal skin
-Intermittent pain, especially with bowel movements, if the tract becomes partially occluded
-A palpable tender lump or swelling around the anus
-Bleeding from the external opening
-Recurrent anal abscesses and drainage.
Signs:
-A visible external opening on the perianal skin, often with granulation tissue or induration around it
-Digital rectal examination may reveal a palpable cord-like tract connecting the external opening to the anal canal
-Tenderness over the fistula tract
-Signs of local inflammation or infection.
Diagnostic Criteria:
-Diagnosis is typically based on a thorough history and physical examination
-The presence of an external opening with associated discharge, coupled with findings on digital rectal examination suggestive of an internal opening, is sufficient for diagnosing a simple low anal fistula
-Imaging is usually reserved for complex or recurrent fistulas.

Diagnostic Approach

History Taking:
-Inquire about the duration and nature of discharge (purulent, bloody, fecal)
-Ask about any history of anal abscess, trauma, inflammatory bowel disease (Crohn's disease), or previous anorectal surgery
-Note any associated pain, fever, or changes in bowel habits
-Assess for any symptoms of fecal incontinence.
Physical Examination:
-Perform a careful perianal inspection to identify the external opening, noting its location and any surrounding inflammation or induration
-Perform a digital rectal examination to assess for tenderness, induration, and the presence of an internal opening
-Gently probe the external opening to assess the direction and depth of the tract, if possible without causing significant pain
-Consider a high-lithotomy position for better visualization.
Investigations:
-For simple low anal fistulas, further investigations are often unnecessary
-However, for complex or recurrent fistulas, or if inflammatory bowel disease is suspected: Magnetic Resonance Imaging (MRI) of the pelvis is the gold standard for mapping fistula tracts and identifying internal openings and abscesses
-Endoscopic ultrasound (EUS) can also be useful
-Anoscopy or rigid sigmoidoscopy may help visualize the internal opening in select cases.
Differential Diagnosis:
-Perianal abscess, hidradenitis suppurativa, pilonidal sinus, anal fissure with secondary infection, and tuberculosis of the anus
-In cases of suspected Crohn's disease, other extra-intestinal manifestations should be sought.

Management

Initial Management:
-For symptomatic low anal fistulas without abscess, fistulotomy is the definitive treatment
-If an abscess is present, incision and drainage of the abscess is the priority before definitive fistula treatment
-Patients should receive adequate analgesia and wound care instructions.
Medical Management:
-Antibiotics are generally not indicated for uncomplicated anal fistulas unless there is significant surrounding cellulitis or abscess
-Prophylactic antibiotics may be considered in immunocompromised patients or those with significant comorbidities
-Management of underlying conditions like Crohn's disease is essential.
Surgical Management:
-Fistulotomy is the primary surgical treatment for low anal fistulas
-The goal is to incise the entire length of the fistula tract from the internal to the external opening, laying it open to granulate
-This involves identifying the fistula tract using a probe or by following the discharge
-The tract is then incised, including the overlying skin, subcutaneous tissue, and the internal and external sphincters if they are within the tract
-Careful hemostasis is achieved
-Postoperative care focuses on wound hygiene and preventing premature closure.
Supportive Care:
-Postoperative care includes regular sitz baths (warm water soaks) to promote healing and hygiene, pain management with analgesics, and stool softeners to prevent straining
-Patients are educated on wound care and to expect some drainage and discomfort for several weeks
-Follow-up appointments are crucial to monitor healing and assess for complications.

Complications

Early Complications:
-Bleeding, pain, infection of the wound, urinary retention, temporary fecal incontinence
-Sepsis can occur if an abscess is missed or inadequately drained.
Late Complications: Fistula recurrence (due to incomplete treatment or missed internal opening), anal stricture, chronic wound, permanent fecal incontinence (more common with high fistulas or extensive sphincter division).
Prevention Strategies:
-Accurate identification of the internal opening is paramount
-Complete division of the fistula tract without sacrificing excessive sphincter muscle is key
-Careful postoperative wound care to prevent premature closure and promote healthy granulation
-Appropriate patient selection and counseling regarding potential risks, especially incontinence.

Prognosis

Factors Affecting Prognosis:
-The success rate of fistulotomy for low anal fistulas is high, typically 90-95%
-Factors influencing prognosis include the accurate identification of the internal opening, the patient's overall health, the absence of underlying conditions like Crohn's disease, and proper surgical technique
-Recurrence is more likely with complex or high fistulas.
Outcomes:
-Most patients experience complete healing of the fistula within 6-8 weeks with minimal long-term sequelae
-The risk of significant anal incontinence is low for well-selected low anal fistulas treated with fistulotomy
-The main concern is recurrence.
Follow Up:
-Regular follow-up appointments are recommended at 2-4 weeks post-operatively and then as needed, to monitor wound healing, assess for signs of recurrence, and address any complications
-Long-term follow-up may be required for patients with associated medical conditions.

Key Points

Exam Focus:
-Fistulotomy is for low anal fistulas
-simple transsphincteric or intersphincteric less than 30% of sphincter
-Identify internal opening accurately
-Lay open the entire tract
-Risk of incontinence increases with sphincter division.
Clinical Pearls:
-Goodsall's rule is crucial for predicting internal opening location in low posterior fistulas
-Always rule out underlying Crohn's disease or other inflammatory conditions
-Ensure adequate pain control and wound hygiene postoperatively.
Common Mistakes:
-Treating a high fistula with fistulotomy, leading to high incontinence risk
-Incomplete division of the fistula tract, leading to recurrence
-Premature closure of the external wound, causing abscess formation
-Misidentifying the internal opening or missing associated abscesses.