Overview

Definition:
-Groin lymph node dissection (inguinal lymphadenectomy) involves the surgical removal of lymph nodes from the inguinal region
-This procedure is often performed for staging and treatment of cancers such as melanoma, squamous cell carcinoma of the lower extremities or perineum, and metastatic disease to the inguinal nodes
-Wound management is critical due to the high risk of complications.
Epidemiology:
-Inguinal lymphadenectomy is a common oncologic procedure
-Complication rates, particularly wound-related issues like infection, seroma formation, and lymphedema, can be significant, affecting up to 50% of patients in some series
-Factors like extent of dissection, patient comorbidities, and adjuvant therapies influence complication rates.
Clinical Significance:
-Effective wound management post-groin dissection is paramount to prevent morbidity, reduce hospital stay, and facilitate timely adjuvant treatments
-Poor wound healing can lead to prolonged recovery, chronic lymphedema, recurrent infections, and psychological distress for the patient
-Understanding management principles is crucial for surgical residents preparing for DNB and NEET SS exams.

Indications

Lymphadenectomy Indications:
-Therapeutic for biopsy-proven inguinal lymph node metastasis
-Staging for high-risk primary tumors (e.g., thin melanomas with sentinel node biopsy positive, vulvar/penile cancers)
-Prophylactic in select high-risk cases where metastasis is suspected but not confirmed.
Contraindications:
-Active widespread infection
-Severe coagulopathy
-Patient refusal
-Advanced metastatic disease precluding survival benefit
-Uncontrolled comorbidities that significantly increase surgical risk.
Preoperative Assessment:
-Detailed history including comorbidities (diabetes, peripheral vascular disease, obesity), previous groin surgery or radiation
-Physical examination to assess skin integrity, presence of infection, and edema
-Nutritional status assessment
-Smoking cessation counseling
-Optimization of glycemic control and anticoagulation status.

Preoperative Preparation

Patient Counseling:
-Informed consent discussing risks, benefits, alternatives, and expected recovery
-Education on wound care, drain management, and physiotherapy
-Realistic expectations regarding swelling and potential for lymphedema.
Anesthesia Considerations:
-General anesthesia or regional anesthesia (spinal/epidural)
-Multimodal analgesia to facilitate early mobilization
-Consider prophylactic antibiotics covering skin flora (e.g., cefazolin).
Surgical Planning:
-Marking of incision lines, considering cosmetic outcomes and potential for flap compromise
-Planning for meticulous hemostasis
-Consideration of drain placement and type
-Techniques to minimize dead space.

Procedure Steps

Incision And Dissection:
-Elliptical incision or curvilinear incision
-Care to preserve saphenous vein if possible
-Dissection of subcutaneous tissue to expose the inguinal ligament superiorly, sartorius muscle laterally, and adductor longus medially
-Removal of lymph nodes en bloc.
Hemostasis:
-Meticulous control of bleeding using electrocautery, ligatures, and topical hemostatic agents
-Small perforators should be coagulated
-A dry field is essential for optimal wound closure.
Wound Closure And Drainage:
-Reapproximation of subcutaneous tissue to obliterate dead space
-Drains (e.g., Jackson-Pratt) are typically placed to prevent seroma formation
-Closure in layers with absorbable sutures
-Skin closure with staples or absorbable sutures.
Dressing:
-Application of sterile dressing, often with a compression element to reduce dead space and prevent hematoma/seroma
-Drainage system management

Postoperative Care

Pain Management:
-Adequate analgesia (opioids, NSAIDs, acetaminophen)
-Consider continuous epidural or peripheral nerve blockade for enhanced pain control and early mobilization.
Drain Management:
-Monitor drain output daily
-Drains are typically removed when output is less than 30 mL in 24 hours
-Early removal can predispose to seroma, late removal to infection.
Mobilization And Physiotherapy:
-Encourage early ambulation to prevent deep vein thrombosis and aid lymphatic drainage
-Gentle range-of-motion exercises for the hip and knee
-Avoid strenuous activity and heavy lifting.
Wound Surveillance:
-Regular inspection of the wound for signs of infection, dehiscence, hematoma, or excessive serous drainage
-Patient education on signs and symptoms of complications to report promptly.

Complications

Early Complications:
-Wound infection: Characterized by erythema, warmth, purulent drainage, fever
-Managed with antibiotics and wound care
-Seroma: Collection of serous fluid in the wound bed
-Management includes aspiration, serial aspirations, or surgical evacuation
-Hematoma: Collection of blood, can lead to infection or delayed healing
-Management may require surgical evacuation
-Wound dehiscence: Separation of wound edges, often due to infection, tension, or poor healing
-Requires surgical re-closure.
Late Complications:
-Chronic lymphedema: Persistent swelling of the limb due to impaired lymphatic drainage
-Managed with compression therapy, physiotherapy, and meticulous skin care
-Lymphocele: Encapsulated collection of lymph
-May require aspiration or marsupialization
-Chronic pain: Persistent neuropathic or musculoskeletal pain in the groin or limb.
Prevention Strategies:
-Meticulous surgical technique with excellent hemostasis
-Obliteration of dead space through careful tissue approximation
-Use of drains
-Postoperative compression
-Patient education on activity restrictions and monitoring
-Prophylactic antibiotics
-Optimizing patient comorbidities (e.g., diabetes control)
-Careful consideration of adjuvant therapies like radiation which can impair healing.

Key Points

Exam Focus:
-High incidence of seroma and lymphedema post-groin dissection
-Importance of meticulous hemostasis and dead space obliteration
-Management of wound infection and dehiscence
-Criteria for drain removal
-Recognition and management of chronic lymphedema.
Clinical Pearls:
-Consider negative pressure wound therapy (NPWT) for complex or high-risk wounds
-Early and aggressive physiotherapy is crucial for lymphedema prevention
-Educate patients that swelling and discomfort can persist for months.
Common Mistakes:
-Inadequate hemostasis leading to hematoma/seroma
-Failure to obliterate dead space
-Premature drain removal
-Insufficient patient education regarding activity restrictions and warning signs of complications
-Aggressive mobilization before wound healing.