Overview

Definition:
-Intraoperative ultrasound (IOUS) is a real-time imaging technique utilized during surgical procedures to visualize anatomical structures, particularly in complex regions like the biliary tree
-It allows surgeons to identify critical structures, assess tissue characteristics, and guide surgical maneuvers with enhanced precision.
Epidemiology:
-IOUS is increasingly employed in hepatobiliary and pancreatic surgery, as well as in laparoscopic cholecystectomies
-Its use is advocated in cases of suspected aberrant biliary anatomy, challenging dissections, or when pre-operative imaging is inconclusive, estimated in 5-15% of elective cholecystectomies and a higher proportion of complex hepatobiliary resections.
Clinical Significance:
-Accurate identification of biliary anatomy intraoperatively is paramount to prevent bile duct injuries, which can lead to significant morbidity, mortality, and long-term complications
-IOUS provides immediate, dynamic visualization, augmenting the surgeon's understanding beyond static pre-operative imaging, thereby improving patient safety and surgical outcomes.

Indications For IOUS Biliary

Suspected Aberrant Anatomy:
-Pre-operative suspicion of variations in cystic duct insertion, common hepatic duct formation, or accessory ducts
-Cases with previous abdominal surgery or inflammation leading to distorted anatomy.
Difficult Cholecystectomy:
-Dense adhesions, inflammation, difficult Calot's triangle dissection, or when identification of the cystic duct and artery is challenging
-Suspected choledocholithiasis requiring intraoperative confirmation or stone clearance.
Biliary Reconstruction: Guiding biliary-enteric anastomoses, assessing ductal patency, and identifying appropriate recipient ducts during reconstructive procedures like Roux-en-Y hepaticojejunostomy.
Liver Resection: Mapping intrahepatic bile ducts and their relationship to tumors or vascular structures during liver resections to prevent inadvertent bile duct transection.
Intraoperative Guidance: Confirming lesion margins, identifying unexpected pathology, or guiding needle placement for drainage or biopsy.

IOUS Technique And Equipment

Equipment Selection:
-Sterilizable ultrasound probes (linear and curvilinear) are essential, typically of higher frequency (7-12 MHz) for superficial structures and lower frequency (3-5 MHz) for deeper visualization
-A sterile sheath or drape is mandatory.
Probe Handling:
-Gentle manipulation with sterile gel or saline
-Avoiding excessive pressure to prevent artifact or displacement of structures
-Constant communication between the sonographer (often the surgeon or assistant) and the operating surgeon.
Scanning Planes:
-Transverse, sagittal, and oblique planes are used to obtain a comprehensive view
-Dynamic scanning with slight probe angulation and patient repositioning can enhance visualization
-Focus on identifying key landmarks like the portal vein, hepatic artery, and their branching patterns relative to the bile ducts.
Image Optimization:
-Adjusting gain, depth, focus, and using Doppler to identify vascular structures and differentiate them from bile ducts
-Harmonic imaging can improve resolution and reduce artifact.

Interpreting Biliary Anatomy With IOUS

Cystic Duct:
-Visualized as a tubular structure connecting the gallbladder to the common hepatic duct
-Its insertion point and angle are critical
-Doppler can help differentiate it from the cystic artery.
Common Hepatic Duct:
-Formed by the confluence of the left and right hepatic ducts
-IOUS can delineate its course and any potential obstructions or tributaries.
Common Bile Duct:
-Formed by the union of the common hepatic duct and the cystic duct
-Its length, diameter, and relation to the pancreatic duct and the duodenum are assessed
-Doppler helps differentiate it from the gastroduodenal artery and portal vein.
Intrahepatic Ducts:
-Visualization of segmental and subsegmental bile ducts, especially crucial in liver resections
-Their branching patterns can be complex and require careful dynamic scanning.
Gallbladder Bed: Assessing for any residual stones or thickened mucosa, and ensuring adequate visualization of the cystic duct stump during cholecystectomy.

IOUS In Specific Surgical Scenarios

Laparoscopic Cholecystectomy:
-Confirming identification of the cystic duct and artery before clipping/ligation
-Visualizing stones in the cystic duct or common bile duct
-Identifying aberrant right hepatic ducts entering the gallbladder bed
-Reducing the risk of bile duct injury.
Open Cholecystectomy:
-Assisting in dissection in cases of severe inflammation or adhesions
-Identifying retracted clips or lost stones
-Guiding common bile duct exploration.
Hepatobiliary Resection:
-Mapping intrahepatic ducts relative to the tumor
-Identifying the origin of major intrahepatic ducts to guide transection planes
-Assessing vascular invasion and its relation to biliary structures.
Pancreaticoduodenectomy:
-Visualizing the common bile duct and its stump during pancreaticojejunostomy
-Assessing ductal patency and identifying any anomalies in the pancreatic duct.

Complications And Limitations Of IOUS

Technical Limitations:
-Limited field of view, operator dependency, potential for artifacts (e.g., reverberation, shadowing), and difficulty in visualizing small structures or stones in tortuous ducts
-Poor acoustic windows due to bowel gas or patient positioning.
Missed Injuries:
-Despite IOUS, bile duct injuries can still occur if critical structures are obscured or if the interpretation is inaccurate
-Complete visualization of all biliary anatomy is not always achievable.
Learning Curve:
-Requires significant practice and experience to master the technique and interpretation
-Correlation with pre-operative imaging and intraoperative findings is essential.
Equipment Failure: Malfunction of the ultrasound machine or probe, or failure of the sterile covering, can necessitate a change in surgical strategy.

Key Points

Exam Focus:
-Understanding the indications for IOUS in biliary surgery
-Recognizing key biliary structures and their sonographic appearance
-Knowing how IOUS helps prevent bile duct injuries
-Awareness of its limitations.
Clinical Pearls:
-Always correlate IOUS findings with pre-operative imaging and direct visualization
-Use Doppler to differentiate vessels from ducts
-Dynamic scanning is crucial for understanding spatial relationships
-If anatomy is unclear, consider intraoperative cholangiography or operative cholangioscopy.
Common Mistakes:
-Mistaking the cystic artery for the cystic duct
-Overlooking small or aberrant ducts
-Insufficient scanning of the entire biliary tree
-Relying solely on IOUS without adequate surgical judgment
-Not recognizing the limitations of the technology.