Overview

Definition:
-The Intraperitoneal Onlay Mesh (IPOM) plus technique is a laparoscopic or open surgical approach for ventral hernia repair where a synthetic or composite mesh is placed directly on the intraperitoneal surface of the abdominal wall, overlying the defect, without being suturalized to the posterior rectus sheath
-The "plus" signifies enhancements such as pre-peritonealization or the use of specific fixation devices to improve outcomes and reduce complications compared to standard IPOM.
Epidemiology:
-Ventral hernias, including incisional and umbilical hernias, are common, occurring in 2-11% of patients undergoing abdominal surgery
-Incisional hernias are the most frequent type, with recurrence rates varying significantly based on repair technique, patient factors, and surgeon experience
-IPOM techniques are widely used for large or complex ventral hernias.
Clinical Significance:
-Ventral hernias can cause pain, disfigurement, and lead to serious complications like incarceration and strangulation, necessitating prompt surgical intervention
-The IPOM plus technique aims to provide durable hernia repair with reduced recurrence and morbidity, making it a crucial topic for surgical residents preparing for DNB and NEET SS examinations.

Indications

Primary Indications:
-Large ventral hernias (>4 cm defect size)
-Recurrent hernias after previous repairs
-Patients with poor tissue quality or multiple comorbidities that preclude tension-free primary repair
-Initial repair of large primary hernias where a mesh is deemed necessary for durability.
Contraindications:
-Active infection at the surgical site or systemically
-Significant contamination of the hernia contents (e.g., enterocutaneous fistula)
-Uncontrolled coagulopathy
-Patients with unrealistic expectations or poor adherence to postoperative instructions
-Incarcerated or strangulated hernias with bowel compromise that requires bowel resection may necessitate alternative techniques or open repair.
Timing Of Repair:
-Elective repair is preferred for asymptomatic or minimally symptomatic hernias to allow for optimal patient preparation and minimize surgical risk
-Emergency repair is indicated for symptomatic hernias with signs of incarceration or strangulation.

Preoperative Preparation

Patient Assessment:
-Thorough history and physical examination to assess hernia characteristics, comorbidities, and prior surgical interventions
-Assessment of nutritional status and smoking history, as these impact wound healing and recurrence
-Optimization of medical conditions like diabetes, hypertension, and anemia.
Imaging:
-Ultrasound or CT scan of the abdominal wall can delineate hernia anatomy, defect size, and presence of adhesions or entrapment
-MRI may be useful in complex cases
-Preoperative imaging is crucial for planning the extent of mesh coverage and fixation strategy.
Anesthesia Considerations:
-General anesthesia is typically required for laparoscopic IPOM plus
-Epidural anesthesia may be an option for some open repairs
-Close monitoring of hemodynamics and ventilation is essential, particularly in patients with respiratory compromise or severe obesity.
Bowel Preparation: Routine bowel preparation is generally not necessary unless there are specific concerns for bowel injury or planned bowel manipulation during open repair.

Procedure Steps

Laparoscopic Approach:
-Port placement in adequate distance from the hernia defect
-Creation of a pre-peritoneal space by dissecting plane between the peritoneum and the transversalis fascia, or within the properitoneal space
-Mobilization and reduction of hernia contents
-Placement of appropriately sized IPOM mesh to overlap the defect by at least 5 cm in all directions
-Fixation of the mesh using tacks, sutures, or fibrin glue, judiciously applied to minimize peritoneal irritation
-Closure of fascial defect if feasible, or overlapping technique.
Open Approach:
-Incision over the hernia sac
-Dissection of the hernia sac from the abdominal wall
-Reduction of hernia contents
-Creation of a pre-peritoneal space by dissecting between the peritoneum and the transversalis fascia
-Placement of IPOM mesh to cover the defect with adequate overlap
-Securing the mesh with sutures or fibrin glue
-Direct fascial closure if possible, or overlapping techniques for large defects.
Mesh Selection:
-Composite meshes (e.g., dual-sided with pore size and barrier properties) are often preferred for IPOM plus to reduce visceral adhesions
-Monofilament polypropylene or ePTFE meshes are also used
-The choice depends on defect size, patient factors, and surgeon preference.
Fixation Methods:
-Various fixation methods are employed, including absorbable or non-absorbable tacks, sutures passed through the mesh and abdominal wall (carefully avoiding bowel injury), or fibrin sealant
-Minimizing fixation points over the visceral side is crucial to prevent adhesions.

Postoperative Care

Pain Management:
-Multimodal pain management is essential, including opioids, NSAIDs, and regional anesthesia (e.g., transversus abdominis plane blocks)
-Adequate pain control facilitates early mobilization and reduces risk of pulmonary complications.
Mobilization And Activity:
-Early ambulation is encouraged
-Restrictions on heavy lifting and strenuous activity for 4-6 weeks are typically advised, with gradual return to normal activities as tolerated
-Patient education on activity restrictions is paramount.
Drainage Management:
-Surgical drains may be used in certain cases, particularly in contaminated fields or extensive dissections, to monitor for fluid collections or bleeding
-Drains are typically removed when output is minimal.
Monitoring For Complications:
-Close monitoring for signs of infection (fever, wound erythema, drainage), seroma, hematoma, mesh migration, and bowel obstruction
-Regular clinical assessment and prompt investigation of any suspicious symptoms.

Complications

Early Complications:
-Seroma formation
-Hematoma
-Wound infection
-Mesh site infection
-Pain
-Nausea and vomiting
-Ileus
-Injury to adjacent organs (bowel, bladder, blood vessels).
Late Complications:
-Chronic mesh infection
-Mesh migration or extrusion
-Hernia recurrence
-Chronic pain
-Adhesions leading to bowel obstruction
-Fistula formation (enterocutaneous or enteromesenteric).
Prevention Strategies:
-Meticulous surgical technique to minimize tissue trauma and dead space
-Judicious use of drains
-Appropriate mesh selection and fixation
-Prophylactic antibiotics
-Preoperative optimization of patient comorbidities
-Patient education on activity restrictions
-Careful adherence to sterile protocols
-Using composite meshes with anti-adhesive barriers.

Prognosis

Recurrence Rates:
-Recurrence rates for IPOM plus techniques are generally lower than open non-mesh repairs, but can still occur
-Studies report recurrence rates ranging from 2% to 15% depending on technique, mesh type, fixation, and patient factors.
Factors Affecting Prognosis:
-Defect size and complexity
-Patient comorbidities (obesity, diabetes, smoking)
-Previous hernia repair attempts
-Surgical technique and surgeon experience
-Mesh type and fixation method
-Postoperative adherence to activity restrictions.
Long Term Outcomes:
-IPOM plus techniques, when performed appropriately, offer durable repair for ventral hernias, restoring abdominal wall integrity and function
-Long-term outcomes are generally favorable, with sustained relief of symptoms and reduced recurrence rates compared to historical methods.

Key Points

Exam Focus:
-Understand the definition of IPOM plus, distinguishing it from standard IPOM
-Recognize indications for mesh repair and specific contraindications
-Key laparoscopic steps include pre-peritoneal dissection and mesh placement with adequate overlap
-Know common early and late complications and their management
-Emphasize the importance of mesh selection and fixation.
Clinical Pearls:
-Achieve a minimum 5 cm overlap of the defect with the mesh
-Be judicious with fixation to minimize bowel adhesions
-Consider composite meshes for better bio-compatibility
-Thorough preoperative optimization of patients is crucial for success
-Aggressive pain management and early mobilization are key to reducing pulmonary complications.
Common Mistakes:
-Insufficient mesh overlap
-Excessive fixation of the mesh directly to bowel
-Inadequate dissection of the pre-peritoneal space
-Ignoring patient comorbidities
-Failure to counsel patients adequately on postoperative restrictions, leading to early recurrence
-Mismanagement of mesh infections.