Overview

Definition:
-Mesenteric volvulus is a surgical emergency characterized by the twisting of the mesentery, leading to obstruction of intestinal blood flow and potential bowel ischemia or infarction
-It can be primary (congenital or idiopathic) or secondary (due to adhesions or tumors).
Epidemiology:
-While rare, affecting approximately 0.04% of patients presenting with bowel obstruction, it accounts for a significant proportion of adult intestinal volvulus, particularly in certain geographic regions
-Incidence peaks in the 3rd to 5th decades of life.
Clinical Significance:
-Mesenteric volvulus is a life-threatening condition requiring prompt diagnosis and surgical intervention to prevent bowel necrosis, perforation, peritonitis, and sepsis
-Early laparoscopic management can lead to improved outcomes and reduced morbidity compared to open surgery.

Clinical Presentation

Symptoms:
-Sudden onset of severe, diffuse abdominal pain
-Nausea and vomiting, often bilious
-Abdominal distension
-Constipation or obstipation
-Passage of blood or mucus per rectum may occur if ischemia is advanced.
Signs:
-Tenderness on abdominal palpation, which can be diffuse or localized
-Guarding and rebound tenderness indicating peritonitis
-Absent bowel sounds or high-pitched tinkling sounds
-Signs of dehydration and hypovolemic shock in advanced cases.
Diagnostic Criteria:
-There are no specific diagnostic criteria beyond clinical suspicion confirmed by imaging
-The diagnosis relies on a high index of suspicion in patients with characteristic symptoms and findings confirmed by imaging modalities.

Diagnostic Approach

History Taking:
-Focus on the acute onset of severe abdominal pain
-Inquire about previous abdominal surgeries, history of constipation, or symptoms suggestive of a mass
-Ask about any predisposing factors like abdominal adhesions or congenital malformations.
Physical Examination:
-Perform a thorough abdominal examination, assessing for distension, tenderness, guarding, rebound tenderness, and bowel sounds
-Evaluate for signs of dehydration and hemodynamic instability
-Assess for hernias.
Investigations:
-Plain abdominal X-rays may show dilated loops of bowel and air-fluid levels, often with an "inversely C-shaped" or "coffee bean" sign
-Contrast-enhanced CT scan is the investigation of choice, revealing a dilated, twisted mesentery, a whirling pattern of mesenteric vessels (whirl sign), and signs of bowel ischemia (bowel wall thickening, mesenteric edema, pneumatosis intestinalis, portal venous gas)
-Laboratory tests include CBC, electrolytes, renal function tests, and lactate levels.
Differential Diagnosis:
-Other causes of acute intestinal obstruction such as adhesions, hernias, intussusception, malignancy, and inflammatory bowel disease should be considered
-Differentiating volvulus from other causes of ischemic bowel, like mesenteric ischemia due to embolism or thrombosis, is crucial.

Management

Initial Management:
-Immediate resuscitation is paramount, including intravenous fluid administration, electrolyte correction, nasogastric tube decompression, and broad-spectrum antibiotics
-Pain management and monitoring of vital signs are essential.
Surgical Management:
-Laparoscopic detorsion and fixation is the preferred initial surgical approach for confirmed mesenteric volvulus without signs of frank gangrene or perforation
-The procedure involves untwisting the mesentery to restore blood flow
-If bowel viability is questionable, a resection and anastomosis may be necessary, potentially requiring conversion to open surgery
-Fixation of the mesentery may be considered to prevent recurrence.
Postoperative Care:
-Close monitoring of vital signs, fluid balance, and abdominal distension
-Gradual reintroduction of oral intake
-Antibiotics may be continued
-Close observation for signs of recurrent obstruction or ischemia
-Early mobilization and prophylactic measures against deep vein thrombosis.
Supportive Care:
-Nutritional support may be required for prolonged periods of ileus
-Management of pain and nausea
-Prevention of complications like pneumonia and urinary tract infections through diligent nursing care and early mobilization.

Complications

Early Complications: Bowel necrosis and perforation, peritonitis, sepsis, intra-abdominal abscess, anastomotic leak if resection is performed, bleeding, prolonged ileus, and wound infection.
Late Complications: Recurrent volvulus, adhesions leading to small bowel obstruction, incisional hernia if open surgery was performed, malnutrition, and psychological distress.
Prevention Strategies:
-Prompt diagnosis and surgical intervention are the primary strategies
-In cases of severe ischemia requiring resection, judicious use of bowel-sparing techniques and careful anastomosis can minimize complications
-Consideration of fixation techniques during primary surgery may help reduce recurrence rates.

Prognosis

Factors Affecting Prognosis:
-The viability of the bowel at the time of surgery is the most critical factor
-Prompt diagnosis and intervention in the absence of significant ischemia lead to a much better prognosis
-The extent of bowel resection and presence of comorbidities also influence outcomes.
Outcomes:
-With timely laparoscopic detorsion and fixation in viable bowel, outcomes are generally good, with reduced hospital stay and faster recovery
-For cases requiring resection, morbidity and mortality rates are higher, depending on the severity of ischemia and patient factors.
Follow Up:
-Patients require close follow-up to monitor for signs of recurrent volvulus, adhesions, or other complications
-Dietary advice and lifestyle modifications may be recommended
-Patients with congenital anomalies might need long-term surveillance.

Key Points

Exam Focus:
-Understand the etiology (primary vs
-secondary), imaging findings (whirl sign on CT), and the critical role of prompt surgical management
-Differentiate symptoms from other causes of acute abdomen
-Emphasize the benefits of laparoscopic approach.
Clinical Pearls:
-Always maintain a high index of suspicion for mesenteric volvulus in patients with sudden, severe abdominal pain and vomiting, especially if risk factors are present
-Early CT scan is crucial for diagnosis
-Laparoscopic detorsion should be attempted if feasible, but do not hesitate to convert to open surgery if bowel viability is uncertain or perforation is suspected.
Common Mistakes:
-Delayed diagnosis due to attributing symptoms to less severe causes
-Inadequate resuscitation before surgery
-Attempting extensive bowel resection laparoscopically without adequate experience or if the patient is unstable
-Failure to consider fixation in appropriate cases to prevent recurrence.