Overview

Definition:
-Open sigmoid colectomy is a surgical procedure involving the removal of a segment of the sigmoid colon through an abdominal incision
-It is typically performed for diseases affecting this part of the large intestine
-The remaining ends of the colon are then reconnected (anastomosis) or brought out as a stoma
-This approach is often chosen when minimally invasive techniques are not feasible or have failed.
Epidemiology:
-Sigmoid colectomy is a common procedure performed for various colonic pathologies, including diverticular disease, colorectal cancer, and inflammatory bowel disease
-The incidence varies geographically and is influenced by the prevalence of these underlying conditions
-Age is a significant factor, with older populations more frequently undergoing this surgery.
Clinical Significance:
-This procedure is crucial for treating serious sigmoid colon pathology that cannot be managed conservatively or endoscopically
-It offers a definitive treatment for conditions like complicated diverticulitis, malignant tumors, and severe ulcerative colitis or Crohn's disease affecting the sigmoid
-Successful execution improves patient outcomes by removing diseased tissue and restoring bowel continuity or function.

Indications

Absolute Indications:
-Sigmoid volvulus with ischemia or perforation
-Sigmoid colon cancer requiring resection
-Complicated sigmoid diverticulitis (e.g., abscess, fistula, obstruction, perforation)..
Relative Indications:
-Recurrent or chronic sigmoid diverticulitis unresponsive to medical management
-Severe sigmoid ischemia without frank perforation
-Benign strictures of the sigmoid colon
-Suspected malignancy not amenable to endoscopic evaluation or treatment.
Contraindications:
-Uncorrected coagulopathy
-Severe systemic illness with prohibitive anesthetic risk
-Widespread intra-abdominal malignancy with unresectable metastases
-Active infection at the operative site (relative contraindication).

Preoperative Preparation

Patient Evaluation:
-Thorough medical history and physical examination
-Assessment of comorbidities (cardiac, pulmonary, renal)
-Nutritional status assessment.
Laboratory Investigations:
-Complete blood count (CBC) to assess for anemia and infection
-Coagulation profile (PT/INR, aPTT)
-Electrolytes and renal function tests (creatinine, urea)
-Liver function tests (LFTs)
-Blood group and cross-matching for potential transfusion.
Imaging:
-Contrast-enhanced CT scan of the abdomen and pelvis to delineate the extent of disease, assess for complications like abscess or fistula, and evaluate for metastatic disease (in malignancy)
-Colonoscopy may be performed preoperatively for cancer staging or to rule out synchronous lesions, if not contraindicated.
Bowel Preparation:
-Mechanical bowel preparation using polyethylene glycol (PEG) or other osmotic laxatives is typically performed to clear the colon
-Antibiotic prophylaxis (e.g., cefazolin with metronidazole or ciprofloxacin with metronidazole) is administered intravenously to reduce the risk of surgical site infection
-Oral antibiotics may also be used as part of the bowel preparation regimen in elective cases.
Anesthesia Considerations:
-General anesthesia with endotracheal intubation is standard
-Epidural analgesia may be considered for postoperative pain control
-Fluid management and hemodynamic monitoring are critical throughout the procedure.

Procedure Steps

Surgical Approach:
-A midline or left paramedian incision is the most common approach for open sigmoid colectomy
-The incision length is determined by the surgeon's preference and the extent of the pathology
-The abdominal cavity is explored to assess for gross pathology, adhesions, and metastatic disease (if indicated).
Sigmoid Mobilization:
-The sigmoid colon is identified and carefully mobilized
-This involves dividing the sigmoid mesentery, starting from the peritoneal reflection of the sigmoid and moving towards the superior rectal artery origin
-Care is taken to ligate and divide the mesenteric vessels to control bleeding
-The dissection proceeds laterally and anteriorly to free the colon from surrounding structures.
Division And Anastomosis:
-The colon is divided proximally and distally to the diseased segment
-The distal margin is typically placed just proximal to the peritoneal reflection of the rectum, or lower if rectal involvement necessitates it
-Staples or sutures are used to divide the bowel and control the lumina
-The freed sigmoid segment is then removed
-The proximal and distal ends are then prepared for anastomosis
-Hand-sewn or stapled techniques can be employed to create the anastomosis, ensuring adequate blood supply to both ends and a leak-free closure
-A double-stapled technique is common for colorectal or colo-anal anastomoses.
Diversion Or Ostomy:
-In cases of high risk for anastomotic leak (e.g., emergency surgery, distal anastomosis, poor patient condition), a temporary diversionary stoma (e.g., loop ileostomy or colostomy) may be created to protect the anastomosis
-This stoma is typically reversed in a subsequent procedure after the anastomosis has healed.

Postoperative Care

Immediate Postoperative Management:
-Patients are monitored in a post-anesthesia care unit (PACU) initially
-Pain management with intravenous analgesics, including patient-controlled analgesia (PCA) or epidural anesthesia, is crucial
-Fluid management and electrolyte balance are maintained with intravenous fluids
-Nasogastric (NG) tube may be placed for gastric decompression, especially if bowel manipulation was extensive or if ileus is a concern.
Monitoring:
-Vital signs are closely monitored for signs of hemodynamic instability, fever, or tachycardia suggestive of infection or complications
-Abdominal examination for distension, tenderness, or signs of peritonitis
-Output from any drains or stomas is carefully recorded
-Serial laboratory tests to monitor for infection and electrolyte imbalances.
Nutrition:
-Early enteral feeding is encouraged as tolerated, typically starting with clear liquids and advancing to a regular diet as bowel function returns
-This promotes gut healing and reduces the risk of parenteral nutrition-related complications
-In cases of prolonged ileus or malabsorption, nutritional support may be required.
Ambulation And Mobilization:
-Early ambulation is vital to prevent deep vein thrombosis (DVT), pulmonary complications, and promote bowel function
-Patients are encouraged to mobilize as soon as they are stable
-Incentive spirometry is used to prevent atelectasis and pneumonia.
Anastomotic Leak Surveillance:
-Patients are educated about signs and symptoms of anastomotic leak, including increasing abdominal pain, fever, tachycardia, abdominal distension, and reduced or absent flatus/stool output
-Any suspicion warrants prompt investigation with imaging (e.g., CT scan) and clinical assessment.

Complications

Early Complications:
-Anastomotic leak: The most serious complication, leading to peritonitis, sepsis, and potential need for reoperation and stoma formation
-Wound infection: Superficial or deep surgical site infection
-Intra-abdominal abscess: Collection of pus within the abdominal cavity
-Bleeding: From mesenteric vessels or at the anastomosis site
-Ileus: Delayed return of bowel function
-Urinary retention
-Pneumonia
-Deep vein thrombosis (DVT) and pulmonary embolism (PE).
Late Complications:
-Anastomotic stricture: Narrowing of the bowel at the anastomosis site, potentially causing obstruction
-Incisional hernia: Protrusion of abdominal contents through a weakened abdominal wall incision
-Chronic pain: Persistent abdominal pain after surgery
-Adhesions: Scar tissue formation that can lead to bowel obstruction
-Stoma-related complications (if a stoma was created): Skin irritation, retraction, prolapse, or stenosis.
Prevention Strategies:
-Meticulous surgical technique with careful ligation of vessels and gentle tissue handling
-Adequate bowel preparation and antibiotic prophylaxis
-Optimal patient selection and preoperative optimization
-Careful anastomosis construction with good blood supply and tension-free closure
-Early recognition and prompt management of postoperative complications
-Prophylaxis against DVT and PE.

Prognosis

Factors Affecting Prognosis:
-The underlying pathology (e.g., cancer stage, severity of diverticulitis), patient's overall health and comorbidities, presence and management of complications (especially anastomotic leak), and the surgeon's experience all significantly influence prognosis
-For colorectal cancer, stage at diagnosis is the most critical prognostic factor.
Outcomes:
-In elective cases for benign conditions, the prognosis is generally excellent, with most patients recovering fully and returning to normal bowel function
-For malignant conditions, prognosis depends on the stage and success of oncological resection and adjuvant therapy
-Morbidity and mortality rates are higher in emergency procedures or when complications arise.
Follow Up:
-Follow-up schedules vary based on the indication for surgery
-For benign conditions, routine follow-up may involve clinical assessment and symptomatic monitoring
-For colorectal cancer, follow-up includes regular clinical examinations, CEA monitoring, and periodic imaging or colonoscopy as per established guidelines (e.g., by ASCRS or national cancer guidelines) to detect recurrence or metachronous lesions.

Key Points

Exam Focus:
-Indications for sigmoid colectomy, particularly for complicated diverticulitis and sigmoid volvulus
-Steps of the surgical procedure, including mobilization, division, and anastomosis techniques
-Management of anastomotic leak and common postoperative complications
-Distinguishing features of sigmoid volvulus on imaging.
Clinical Pearls:
-In cases of sigmoid volvulus, untwisting the volvulus laparoscopically or endoscopically (detorsion) can sometimes be attempted prior to resection if there are no signs of ischemia or perforation, but this is an adjunct to surgery
-Be vigilant for signs of impending perforation in acute diverticulitis, which mandates urgent surgical intervention
-Always assess the entire colon for synchronous lesions when dealing with colorectal cancer
-Consider a temporary stoma in high-risk anastomosis patients.
Common Mistakes:
-Inadequate bowel preparation leading to increased infection risk
-Insufficient mobilization of the sigmoid colon, leading to tension on the anastomosis
-Poorly identified or ligated mesenteric vessels causing intraoperative bleeding
-Delayed diagnosis and management of anastomotic leak
-Failure to consider or adequately investigate for synchronous lesions in cases of malignancy.