Overview

Definition:
-Penile fracture refers to a tear in the tunica albuginea, the fibrous sheath encasing the corpus cavernosum, typically occurring during forceful penile bending while erect
-It is a urological emergency requiring prompt surgical intervention to minimize long-term complications.
Epidemiology:
-Penile fracture is rare, with an incidence estimated between 1 in 1,600 to 1 in 30,000 male emergency room visits
-It most commonly occurs in sexually active men aged 15-55 years, with peak incidence in the 20-40 year age group
-The mechanism is usually aggressive sexual intercourse or penile manipulation during masturbation.
Clinical Significance:
-Failure to promptly diagnose and surgically repair penile fracture can lead to significant long-term morbidity, including erectile dysfunction, penile curvature (Peyronie's disease), and painful erections
-Timely surgical intervention is crucial for optimal functional recovery and patient satisfaction.

Clinical Presentation

Symptoms:
-A sudden, audible "snap" or "crack" sensation during intercourse
-Immediate severe penile pain
-Rapid detumescence (loss of erection)
-Significant penile swelling and ecchymosis (bruising), often described as a "eggplant deformity." Hematuria (blood in urine) if the urethra is also involved
-Inability to urinate due to urethral injury or severe swelling.
Signs:
-Gross penile deformity, typically a deviation from the midline
-Marked penile swelling and discoloration, often extending to the scrotum and perineum
-Palpable defect or fluctuance along the penile shaft
-Tenderness on palpation
-Urethral bleeding from the meatus or signs of urethral disruption (e.g., urinary extravasation).
Diagnostic Criteria:
-The diagnosis is primarily clinical, based on a history of the characteristic mechanism of injury and the presence of a palpable defect in the tunica albuginea during erect or semi-erect state
-Imaging is generally not required for diagnosis if a clear defect is felt, but may be used in equivocal cases.

Diagnostic Approach

History Taking:
-Detailed history of the injury mechanism is paramount
-ask about sexual activity, penile position, and any audible or palpable sensations
-Inquire about prior penile trauma, surgery, or history of erectile dysfunction or Peyronie's disease
-Assess for any concurrent injuries.
Physical Examination:
-A thorough examination of the external genitalia is essential
-While not always feasible or necessary in a conscious patient, an artificial erection test (e.g., using saline injection into the corpus cavernosum) can help localize the injury and assess the extent of the tear if the diagnosis is uncertain
-Examine for urethral meatal bleeding or hematoma extension.
Investigations:
-No routine laboratory investigations are required for the initial diagnosis
-However, urinalysis may reveal hematuria if the urethra is injured
-Ultrasound of the penis can sometimes delineate the tear in the tunica albuginea and corpus cavernosum, but its sensitivity is operator-dependent and it should not delay surgical intervention
-Retrograde urethrography is indicated if urethral injury is suspected (e.g., meatal bleeding, inability to void).
Differential Diagnosis:
-Hematoma formation without a true tunica albuginea tear (e.g., from direct blunt trauma)
-Fournier's gangrene (though usually associated with infection and rapidly progressing necrosis)
-Penile priapism (persistent erection)
-Trauma to the scrotum or perineum.

Management

Initial Management:
-Immediate referral to a urologist or emergency surgeon
-Pain control with analgesics
-Broad-spectrum intravenous antibiotics to cover gram-negative organisms and anaerobes, especially if urethral injury is suspected
-Catheterization should be avoided if possible, especially if urethral injury is a concern
-suprapubic catheterization may be necessary if urinary retention is present.
Medical Management:
-Primarily supportive, focusing on pain relief and infection prophylaxis
-No medical management can repair a ruptured tunica albuginea.
Surgical Management:
-Emergency surgical exploration and repair is the gold standard for penile fracture
-Indications include a palpable tear in the tunica albuginea and/or corpus cavernosum
-The procedure involves longitudinal incision along the penile shaft to expose the tunica albuginea
-The tear(s) are then meticulously repaired with absorbable or non-absorbable sutures (e.g., 3-0 or 4-0 polydioxanone or Prolene)
-If the urethra is injured, it should also be repaired primarily
-Following tunical repair, a saphenous vein graft or dura mater graft may be considered for very large or multiple defects, though this is less common
-Hemostasis is achieved, and a drain may be placed
-A compressive dressing is applied post-operatively.
Supportive Care:
-Close monitoring for signs of infection, hematoma, or wound dehiscence
-Pain management
-Counsel on sexual activity restrictions (typically 6-8 weeks)
-Antibiotic prophylaxis continuation as per local protocols
-Encouragement of early ambulation.

Complications

Early Complications:
-Hematoma formation
-Wound infection
-Dehiscence of the surgical repair
-Urinary retention
-Urethral injury exacerbation.
Late Complications:
-Erectile dysfunction (persistent or new-onset)
-Penile curvature (Peyronie's disease)
-Painful erections
-Loss of penile sensation
-Fibrous plaque formation within the corpus cavernosum
-Sexual dissatisfaction.
Prevention Strategies:
-Prompt and meticulous surgical repair of the tunica albuginea is the most crucial preventive measure against late complications
-Careful handling of tissues during surgery
-Adherence to post-operative instructions regarding sexual abstinence
-Early identification and management of wound infections.

Prognosis

Factors Affecting Prognosis:
-Timeliness of surgical intervention
-Extent and number of tears in the tunica albuginea
-Presence and severity of associated urethral injury
-Patient's pre-injury erectile function
-Adherence to post-operative rehabilitation protocols.
Outcomes:
-With prompt surgical repair, the majority of patients have a good prognosis for regaining satisfactory erectile function and avoiding significant long-term sequelae
-Studies report success rates of 70-90% for preserving erectile function
-However, some degree of penile curvature or dyspareunia can persist in a minority of patients.
Follow Up:
-Regular follow-up appointments are essential, typically at 1 week, 1 month, and 3-6 months post-operatively
-These visits assess wound healing, monitor for complications, and evaluate erectile function
-Patients should be advised to avoid sexual activity for at least 6-8 weeks and to report any new or worsening symptoms immediately.

Key Points

Exam Focus:
-Penile fracture is a tear of the tunica albuginea
-a surgical emergency
-The classic history is a "snap" during intercourse followed by pain and detumescence
-Surgical repair involves suturing the tunica albuginea
-Prompt repair is key to preventing erectile dysfunction and Peyronie's disease.
Clinical Pearls:
-Always consider penile fracture in any male patient presenting with penile trauma and rapid detumescence
-A palpable defect is usually pathognomonic
-Do not delay surgery
-ultrasound is an adjunct, not a substitute for exploration
-Ensure adequate antibiotic coverage, especially if urethral injury is suspected.
Common Mistakes:
-Delaying surgical intervention due to uncertainty or preference for conservative management
-Inadequate exploration and repair of all tunical tears
-Failure to consider and manage associated urethral injuries
-Insufficient post-operative counseling regarding sexual restrictions.