Overview

Definition:
-A pilonidal sinus is an acquired condition characterized by a chronic inflammatory condition in the natal cleft, typically containing hair fragments and debris, leading to the formation of sinuses or abscesses
-Excision with flap reconstruction, particularly the Karydakis technique, aims for complete removal of the sinus and surrounding diseased tissue with primary closure using a lateralized flap to reduce recurrence.
Epidemiology:
-It predominantly affects young adults, with a male predominance (3:1 to 4:1)
-Incidence is higher in Caucasians
-Risk factors include obesity, deep natal cleft, sedentary lifestyle, and thick hair growth.
Clinical Significance:
-Pilonidal sinus disease is a common surgical problem causing significant morbidity, pain, and disability
-Recurrence rates are high with traditional open excision methods
-The Karydakis flap technique offers improved outcomes with lower recurrence rates and faster healing, making it a critical procedure for surgical residents to understand and master for DNB and NEET SS preparation.

Clinical Presentation

Symptoms:
-Acute presentation often includes severe pain and swelling in the natal cleft, suggestive of an abscess
-Chronic symptoms include recurrent discharge (serous, purulent, or bloody), discomfort, and pain, especially with prolonged sitting
-A palpable lump may be present
-Recurrent infections can lead to tunneling and multiple external openings.
Signs:
-A midline dimple or pits in the natal cleft, often with protruding hairs
-Palpation may reveal tenderness, fluctuance (if abscessed), or induration
-External openings of sinus tracts are visible, often with surrounding inflammation or granulation tissue
-Edema and erythema may be present if acutely infected.
Diagnostic Criteria:
-Diagnosis is primarily clinical, based on characteristic symptoms and physical examination findings
-There are no formal diagnostic criteria
-however, the presence of a midline natal cleft sinus tract with associated hair, discharge, or recurrent infection is pathognomonic.

Diagnostic Approach

History Taking:
-Key history points include onset and duration of symptoms, nature of discharge, presence of pain, previous treatments (conservative or surgical), history of trauma to the area, and occupational/lifestyle factors (e.g., prolonged sitting, physical labor)
-Inquire about fever or systemic symptoms if acute infection is suspected.
Physical Examination:
-A thorough examination of the natal cleft is essential
-Inspect for dimples, pits, sinus openings, hair extrusion, erythema, and swelling
-Palpate for tenderness, induration, and fluctuance
-Assess the extent of the sinus tract if possible
-Avoid aggressive palpation of acutely inflamed or abscessed areas.
Investigations:
-Generally, no investigations are required for a typical diagnosis
-In complex cases, recurrent disease, or suspected malignancy (rare), imaging like MRI can delineate the extent of tracts and identify associated pathology
-A complete blood count (CBC) may be useful to assess for signs of acute infection.
Differential Diagnosis:
-Differential diagnoses include hidradenitis suppurativa, anal fistula, coccygeal osteomyelitis, superficial folliculitis, sebaceous cysts, and spinal dermoid sinus
-Distinguishing features involve the specific location (natal cleft), characteristic hair findings, and pattern of discharge.

Management

Initial Management:
-For acute abscesses, incision and drainage (I&D) are the initial steps
-This provides symptomatic relief
-Conservative management with local hygiene and antibiotics may be considered for very mild superficial infections or as an adjunct to I&D, but it does not address the underlying pathology.
Medical Management:
-Antibiotics are primarily used to treat acute infections or cellulitis associated with pilonidal sinus
-Broad-spectrum antibiotics targeting skin flora (e.g., Staphylococci and Streptococci) are typically prescribed
-Examples include cephalexin 500 mg orally four times daily or clindamycin 300 mg orally three times daily for 7-10 days
-This is usually an adjunct to surgical drainage for abscesses.
Surgical Management:
-The Karydakis flap is the gold standard for definitive treatment
-It involves wide excision of the sinus, subcutaneous tissue, and any tracts, extending to healthy tissue
-The natal cleft is then flattened by excising a portion of the skin and subcutaneous tissue from the affected side and creating a rotation-advancement flap from the contralateral side to close the defect
-This technique aims to eliminate the deep natal cleft predisposing to recurrence.
Postoperative Care:
-Wound care is crucial
-Patients are advised to keep the area clean and dry, avoiding prolonged sitting for the initial period
-Pain management is essential
-Antibiotics may be prescribed prophylactically or if signs of infection develop
-Mobilization is encouraged to prevent deep vein thrombosis
-Regular follow-up is required to monitor wound healing and detect any signs of recurrence.

Complications

Early Complications:
-Wound infection, dehiscence, seroma formation, hematoma, flap necrosis, and delayed wound healing
-Pain is a significant early complication requiring adequate analgesia.
Late Complications:
-Recurrence of the pilonidal sinus disease is the most significant late complication, occurring more frequently with less radical excision techniques
-Chronic pain and contour deformities are also possible.
Prevention Strategies:
-Meticulous surgical technique with wide excision, complete removal of all sinus tracts, and effective flap closure are paramount
-Postoperative wound care, hygiene, and avoidance of prolonged sitting in the early period help prevent complications and recurrence
-Hair removal in the natal cleft area post-healing is often recommended.

Prognosis

Factors Affecting Prognosis:
-The success rate is heavily dependent on the thoroughness of the excision and the technique used
-The Karydakis flap has shown significantly lower recurrence rates (typically <5%) compared to simple excision or other flap techniques.
Outcomes:
-With successful Karydakis flap surgery, patients can expect a durable cure with minimal risk of recurrence and a satisfactory cosmetic outcome
-Most patients return to normal activities within 2-4 weeks.
Follow Up:
-Follow-up appointments are scheduled at 1 week, 1 month, and 3-6 months post-operatively, or as needed
-The purpose is to monitor wound healing, assess for any signs of infection or recurrence, and ensure patient satisfaction
-Long-term self-monitoring for any new symptoms is important.

Key Points

Exam Focus:
-Understand the anatomy of the natal cleft and the pathogenesis of pilonidal sinus
-Differentiate between acute abscess and chronic disease
-Know the indications and contraindications for Karydakis flap
-Recognize early and late complications
-The Karydakis flap is favored for its low recurrence rate due to elimination of the natal cleft depth.
Clinical Pearls:
-Always perform a thorough examination in good lighting
-When performing Karydakis, ensure adequate flap mobilization and tension-free closure
-Advise patients on the importance of hygiene and avoiding prolonged sitting post-operatively
-Remember that recurrence is a significant issue, so radical excision is key.
Common Mistakes:
-Incomplete excision of sinus tracts and associated diseased tissue
-Failure to create a tension-free closure
-Not flattening the natal cleft sufficiently
-Inadequate postoperative advice regarding hygiene and activity
-Misdiagnosing pilonidal sinus as a simple boil or other perianal pathology.