Overview

Definition: A popliteal artery aneurysm (PAA) is a localized, permanent dilation of the popliteal artery, typically defined as a diameter greater than 1.5 times the adjacent normal artery or exceeding 2 cm.
Epidemiology:
-PAAs are the most common peripheral arterial aneurysms, accounting for 70% of all peripheral aneurysms
-They are strongly associated with abdominal aortic aneurysms (AAAs), occurring in 40-50% of patients with AAAs
-The incidence is higher in men and older individuals, particularly those with atherosclerotic risk factors like smoking, hypertension, and hyperlipidemia
-Spontaneous rupture is rare but associated with high morbidity and mortality.
Clinical Significance:
-PAAs pose a significant risk of limb-threatening complications, including thrombosis, distal embolization leading to acute limb ischemia, and, rarely, rupture
-Prompt diagnosis and appropriate management are crucial to prevent devastating outcomes and preserve limb function for surgical residents preparing for DNB and NEET SS examinations.

Clinical Presentation

Symptoms:
-Asymptomatic presentation is common, discovered incidentally
-Symptomatic presentation may include: Pulsatile mass in the popliteal fossa
-Pain in the calf or foot, often exacerbated by activity (claudication)
-Acute limb ischemia due to thrombosis or embolization, characterized by sudden onset of severe pain, pallor, pulselessness, paralysis, and poikilothermia
-Rest pain, non-healing ulcers, or gangrene in severe cases.
Signs:
-A palpable, expansile pulsatile mass in the popliteal fossa, best appreciated with the knee extended and the patient prone
-Diminished or absent distal pulses (dorsalis pedis, posterior tibial)
-Signs of acute limb ischemia if thrombosed or embolized
-Neurological deficits if peroneal nerve is compressed by the aneurysm.
Diagnostic Criteria:
-No specific diagnostic criteria exist, but a diagnosis is typically made based on imaging findings
-A diameter >2 cm in the popliteal artery, or a >50% increase compared to the adjacent segment, is generally considered aneurysmal
-For surgical intervention, a threshold diameter of 2 cm is often used, or symptomatic aneurysms regardless of size.

Diagnostic Approach

History Taking:
-Detailed history of cardiovascular risk factors: smoking, hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, previous AAA
-History of claudication or rest pain
-Any symptoms suggestive of acute limb ischemia
-Family history of aneurysms
-Previous vascular interventions.
Physical Examination:
-Careful palpation of the popliteal fossa for a pulsatile mass
-Auscultation for bruits over the mass
-Assessment of distal pulses in the lower extremities (femoral, popliteal, dorsalis pedis, posterior tibial)
-Neurological examination of the foot and lower leg
-Assessment for signs of peripheral neuropathy or ischemia.
Investigations:
-Duplex ultrasonography (USG): The primary non-invasive imaging modality for diagnosis and surveillance
-It can accurately measure aneurysm diameter, assess flow patterns, and detect thrombus
-Computed tomography angiography (CTA): Provides detailed anatomical information, useful for planning surgical or endovascular repair, especially for complex anatomy or suspected complications
-Magnetic resonance angiography (MRA): An alternative to CTA, useful in patients with contrast allergies or renal dysfunction
-Arteriography: Historically used but now less common as a primary diagnostic tool
-may be used intraoperatively or for planning complex interventions.
Differential Diagnosis:
-Baker's cyst (popliteal cyst): Can mimic a pulsatile mass but lacks true expansile pulsation and is often associated with underlying knee pathology
-Femoral artery aneurysm: May be confused if palpation is not meticulous
-Lymphadenopathy: Usually firm and non-pulsatile
-Arteriovenous fistula: Presents with a palpable thrill and continuous bruit.

Management

Indications For Intervention:
-Symptomatic aneurysm: Acute limb ischemia, nerve compression, rupture
-Asymptomatic aneurysm: Diameter >2.0 cm, or associated with significant risk factors for complications
-Aneurysm with thrombus, especially if protruding or mobile
-Association with distal embolization.
Surgical Management:
-Open surgical repair: The traditional gold standard
-Typically involves ligation of the aneurysm and bypass grafting using autogenous saphenous vein or prosthetic material (e.g., PTFE)
-The aneurysm sac is either excised or excluded
-Key steps include proximal and distal control of the popliteal artery, thrombectomy, and graft placement
-Endovascular repair (EVAR): Increasingly used, especially for patients unsuitable for open surgery
-Involves deployment of a stent-graft to exclude the aneurysm sac from circulation
-Typically accessed via transfemoral approach
-Requires suitable aneurysm anatomy for stent-graft sealing.
Preoperative Preparation:
-Thorough cardiovascular assessment and optimization
-Risk stratification for anesthesia and surgery
-Optimization of comorbidities (hypertension, diabetes)
-Smoking cessation advice
-Preoperative duplex ultrasound and/or CTA to delineate anatomy and plan the approach
-Antibiotic prophylaxis.
Postoperative Care:
-Close monitoring for signs of bleeding, infection, or graft occlusion
-Pain management
-Early mobilization
-Antithrombotic therapy (aspirin, clopidogrel) as per protocol
-Serial duplex ultrasound surveillance to assess graft patency and monitor for endoleaks (in EVAR).
Supportive Care:
-Management of risk factors (smoking cessation, statin therapy, antihypertensives)
-Wound care
-Pain control
-Deep vein thrombosis prophylaxis
-Nutritional support.

Complications

Early Complications:
-Graft thrombosis or occlusion
-Distal embolization
-Acute limb ischemia
-Bleeding from suture lines or graft
-Infection of the graft
-Nerve injury (e.g., peroneal nerve palsy)
-Deep vein thrombosis.
Late Complications:
-Graft degeneration or pseudoaneurysm formation
-Distal embolization from thrombus within the aneurysm sac (if not completely excluded)
-Stenosis or occlusion of the graft
-Chronic limb ischemia
-Endoleak (in EVAR).
Prevention Strategies:
-Meticulous surgical technique, including adequate graft length and securing, proper suture techniques, and careful handling of the artery
-Use of autogenous vein for bypass when possible
-Appropriate antithrombotic therapy
-Careful patient selection for EVAR and appropriate stent-graft sizing
-Aggressive surveillance with duplex ultrasound.

Prognosis

Factors Affecting Prognosis:
-Presence and severity of limb ischemia
-Patient's overall health and comorbidities
-Success of the repair (graft patency)
-Promptness of diagnosis and intervention
-Type of repair (open vs
-endovascular).
Outcomes:
-Successful repair leads to excellent limb salvage rates
-Open repair generally has high long-term patency and durability
-Endovascular repair offers a less invasive option with good short- to mid-term results, but long-term durability may be lower than open repair, especially in certain anatomies
-Unrepaired symptomatic aneurysms have a high risk of limb loss.
Follow Up:
-Regular clinical and duplex ultrasound follow-up is essential
-For open repair, annual follow-up is typically recommended to monitor graft patency
-For EVAR, more frequent follow-up is required initially to detect endoleaks and monitor graft integrity, usually with duplex ultrasound and potentially CTA or MRA
-Follow-up should continue for the lifetime of the patient.

Key Points

Exam Focus:
-Popliteal aneurysms are the most common peripheral aneurysms and are strongly associated with AAAs
-Management is indicated for symptomatic aneurysms or asymptomatic aneurysms >2 cm
-Duplex US is the primary diagnostic tool
-Management options include open surgical repair with bypass and endovascular exclusion.
Clinical Pearls:
-Always palpate the popliteal fossa in patients with peripheral vascular disease or AAA
-Suspect popliteal aneurysm if a pulsatile mass is found
-Differentiate from Baker's cyst based on pulsation
-Endovascular repair requires careful anatomical assessment for suitability.
Common Mistakes:
-Failure to adequately assess distal pulses
-Mistaking a Baker's cyst for a popliteal aneurysm
-Inadequate imaging leading to poor surgical planning
-Not providing adequate antithrombotic therapy post-repair
-Insufficient long-term surveillance for graft issues or endoleaks.