Overview

Definition:
-Prehabilitation is a multimodal, preoperative intervention designed to improve a patient's functional capacity and physiological reserve before undergoing major surgery
-It aims to optimize health status and reduce the risk of postoperative complications, thereby enhancing recovery
-This approach is proactive, focusing on enhancing fitness before the surgical insult.
Epidemiology:
-The incidence of complications after major surgery can be significant, affecting up to 30% of patients
-Factors like frailty, comorbidities, and poor functional status are associated with higher complication rates and prolonged hospital stays
-Prehabilitation is gaining traction globally as a strategy to mitigate these risks, particularly in frail and elderly populations undergoing complex procedures.
Clinical Significance:
-For surgical residents preparing for DNB and NEET SS examinations, understanding prehabilitation is crucial
-It represents a paradigm shift from traditional "rehabilitation" (post-surgery) to a proactive, evidence-based approach that directly impacts patient outcomes, length of hospital stay, and healthcare costs
-Mastering these principles enhances clinical decision-making and improves patient care quality.

Components Of Prehabilitation

Nutritional Optimization:
-Assessing and correcting nutritional deficiencies
-Providing targeted nutritional support, including protein and micronutrient supplementation
-Often guided by a dietitian
-Identification of sarcopenia and intervention with protein and vitamin D is key.
Physical Exercise:
-Tailored exercise programs to improve cardiorespiratory fitness, muscle strength, and endurance
-This can include aerobic exercises, resistance training, and flexibility exercises
-A gradual increase in intensity and duration is recommended, often supervised by a physiotherapist.
Psychological Support:
-Addressing anxiety, depression, and stress related to surgery through counseling, relaxation techniques, and patient education
-Building a positive mindset and coping mechanisms is vital for patient compliance and recovery.
Anemia Management:
-Identification and treatment of anemia using iron supplementation (oral or IV) or erythropoiesis-stimulating agents
-Optimal hemoglobin levels can improve oxygen delivery to tissues, aiding recovery.
Smoking Cessation:
-Encouraging and supporting smoking cessation for at least 4-6 weeks before surgery to reduce respiratory complications
-Nicotine replacement therapy may be considered.
Alcohol Cessation: Managing alcohol dependence and withdrawal symptoms to prevent complications like delirium tremens and infections.
Glycemic Control: Optimizing blood glucose levels in diabetic patients to reduce surgical site infections and improve wound healing.

Indications And Contraindications

Indications:
-Patients undergoing major elective surgery, especially those at high risk for complications due to age, frailty, comorbidities (e.g., COPD, cardiovascular disease, diabetes), or poor functional status
-Procedures like major abdominal surgery, thoracic surgery, and orthopedic surgery often benefit
-Patients with low physical activity levels are prime candidates.
Contraindications:
-Absolute contraindications are rare and typically relate to immediate life-saving surgery where prehabilitation is not feasible
-Relative contraindications may include severe, acute illness, unmanaged sepsis, or patient refusal
-The decision to implement prehabilitation is individualized based on risk-benefit assessment.

Assessment And Monitoring

Functional Assessment:
-Evaluating baseline functional capacity using tools like the 6-minute walk test, handgrip strength, or validated frailty indices
-This helps tailor the prehabilitation program and track progress.
Nutritional Assessment:
-Assessing nutritional status through anthropometric measurements, biochemical markers (e.g., albumin, prealbumin), and dietary recall
-Tools like the Mini Nutritional Assessment (MNA) can be useful.
Cardiopulmonary Assessment: Evaluating cardiorespiratory fitness through spirometry, ECG, and exercise tolerance tests as indicated by patient history and comorbidities.
Psychological Assessment:
-Screening for anxiety, depression, and coping abilities using validated questionnaires
-Identifying psychological barriers to adherence.
Monitoring Progress:
-Regular follow-up to assess adherence to the program, monitor physiological parameters, and adjust interventions as needed
-Communication between the multidisciplinary team is essential
-Improvement in functional tests indicates successful prehabilitation.

Impact On Surgical Outcomes

Reduced Complications: Evidence suggests prehabilitation can significantly reduce the incidence of various postoperative complications, including pneumonia, cardiovascular events, delirium, and surgical site infections.
Shorter Hospital Stay: Patients undergoing prehabilitation often experience faster recovery, leading to shorter lengths of hospital stay and reduced healthcare resource utilization.
Improved Functional Recovery: Enhanced preoperative functional capacity translates to better postoperative physical function, faster return to independence, and improved quality of life.
Cost Effectiveness: While requiring upfront investment, prehabilitation has been shown to be cost-effective by reducing complications, readmissions, and length of stay, leading to overall savings in healthcare expenditure.

Key Points

Exam Focus:
-Prehabilitation is a proactive strategy to optimize patients before surgery, focusing on exercise, nutrition, and psychological support
-It differs from rehabilitation (post-surgery)
-Key components include improving cardiorespiratory fitness, muscle strength, nutritional status, and psychological well-being
-Aim is to enhance physiological reserve and reduce postoperative morbidity
-High-yield for DNB/NEET SS exam questions on perioperative care and ERAS protocols.
Clinical Pearls:
-Start prehabilitation as early as possible, ideally weeks to months before surgery
-A multidisciplinary team approach is essential for success
-Individualize the program based on patient assessment and surgical procedure
-Early identification and management of anemia is crucial
-Encourage patient engagement and adherence through clear communication and support.
Common Mistakes:
-Treating prehabilitation as an afterthought or solely a physiotherapist's responsibility
-Underestimating the psychological component
-Failing to adequately assess and address nutritional status
-Inconsistent monitoring and program adjustment
-Not involving the patient in goal-setting, leading to poor adherence.