Overview

Definition:
-The Wise pattern mastectomy, also known as the inframammary fold pattern or Wise pattern reduction pattern mastectomy, is a surgical technique used for breast cancer treatment and breast reduction
-It involves a curvilinear incision in the inframammary fold (IMF) that extends upwards towards the nipple-areola complex (NAC), creating a "keyhole" or "anchor" shaped scar
-This approach allows for extensive skin and glandular resection while facilitating optimal aesthetic outcomes and oncologic safety.
Epidemiology:
-While not a standalone disease entity, Wise pattern mastectomy is employed in a significant proportion of breast cancer surgeries requiring mastectomy, particularly in cases of macromastia or ptosis where traditional breast-sparing techniques are insufficient or undesirable
-Its use in breast reduction surgeries is also widespread, addressing concerns of gigantomastia and related symptoms.
Clinical Significance:
-This technique is crucial for surgeons managing breast cancer in patients with large or pendulous breasts, enabling adequate tumor resection with improved cosmetic results compared to standard transverse or superior pedicle techniques
-It is also vital for alleviating symptoms associated with macromastia, such as back and neck pain, and improving quality of life
-Understanding this pattern is essential for DNB and NEET SS candidates preparing for breast surgery viva voce and practical examinations.

Indications

Oncologic Indications:
-Mastectomy for breast cancer in patients with macromastia or significant breast ptosis
-Tumors located centrally or in the inferior quadrants that necessitate significant glandular tissue removal
-Patients desiring breast conservation but having macromastia that would lead to poor aesthetic outcome with lumpectomy alone and requiring a mastectomy with immediate or delayed reconstruction.
Reconstructive Indications:
-Reduction mammoplasty in cases of gigantomastia or symptomatic macromastia where a significant reduction in breast volume is desired
-Correction of breast asymmetry with significant ptosis where a standard reduction is not sufficient.
Contraindications:
-Active local infection
-Uncontrolled comorbidities that preclude extensive surgery
-Severe coagulopathy
-Neoadjuvant chemotherapy in certain protocols where definitive surgery timing is critical
-Patients unwilling or unable to comply with postoperative care.

Preoperative Preparation

Patient Assessment:
-Thorough history and physical examination, including assessment of breast size, ptosis grade, presence of comorbidities, and patient expectations
-Detailed discussion of surgical risks, benefits, alternatives, and expected outcomes, including scar appearance
-Preoperative photographs are essential for documentation and planning.
Imaging And Biopsies:
-Mammography, ultrasound, and MRI as indicated for tumor staging
-Biopsy confirmation of malignancy
-Sentinel lymph node biopsy planning if indicated.
Surgical Planning:
-Marking the planned incision lines, NAC position, and extent of skin and glandular resection
-Consideration for contralateral symmetrization mastopexy or reduction in select cases
-Antibiotic prophylaxis initiated preoperatively.

Procedure Steps

Anesthesia And Positioning:
-General anesthesia is typically used
-The patient is positioned in a supine position with arms abducted
-Careful draping to allow access to the entire breast and axilla.
Incision And Dissection:
-The Wise pattern incision is meticulously marked, extending along the IMF and superiorly towards the NAC
-Dissection is carried down to the pectoralis fascia
-Subcutaneous flaps are elevated, preserving adequate thickness to ensure vascularity and minimize dehiscence
-The NAC is typically incorporated within the resected specimen or preserved based on tumor proximity and technique.
Glandular Excision And Hemostasis:
-The breast parenchyma is excised en bloc with the skin, ensuring adequate margins for oncologic safety
-Hemostasis is meticulously achieved using electrocautery and ligation of vessels
-Lymph node dissection or sentinel lymph node biopsy is performed as per oncologic indications.
Breast Reshaping And Closure:
-The remaining glandular tissue is reshaped to create a more aesthetically pleasing breast mound
-The superior flap is advanced downwards to meet the inferior flap, and the skin is closed in multiple layers, often with buried sutures and a final skin closure
-Drains are typically placed to manage seroma
-The NAC is reconstructed or repositioned if preserved
-Immediate reconstruction with implants or autologous tissue may be performed concurrently.
Scar Management:
-The resulting scar is a curvilinear incision along the IMF and a vertical limb extending superiorly
-Scar management strategies are discussed with the patient postoperatively.

Postoperative Care

Pain Management:
-Adequate analgesia is provided, often with a combination of oral and intravenous medications
-Patient-controlled analgesia (PCA) may be used in the immediate postoperative period.
Drain Management:
-Surgical drains are typically in place and are removed when the output is less than 20-30 ml per 24 hours
-Monitoring for drain output is crucial.
Wound Care:
-Dressing changes as per protocol
-Monitoring for signs of infection, dehiscence, or hematoma
-Application of surgical bras or compressive dressings to support the breast mound and reduce edema.
Activity Restrictions:
-Patients are advised to avoid strenuous activity, heavy lifting, and sleeping on their stomach for several weeks
-Gradual return to normal activities is encouraged as tolerated
-Arm movement may be restricted initially to protect the wound and flaps.

Complications

Early Complications:
-Hematoma
-Seroma
-Wound infection
-Wound dehiscence
-Partial or complete flap necrosis, particularly of the NAC or skin flaps
-Axillary webbing
-Persistent pain.
Late Complications:
-Scar hypertrophy or keloid formation
-Asymmetry
-Loss of nipple sensation
-Chronic lymphedema (if axillary dissection performed)
-Unfavorable aesthetic outcome
-Recurrence of disease
-Implant-related complications if immediate reconstruction is performed.
Prevention Strategies:
-Meticulous surgical technique with preservation of adequate vascularity to skin flaps
-Careful hemostasis
-Appropriate drain placement and management
-Judicious use of compressive dressings
-Patient education on postoperative care and activity restrictions
-Prophylactic antibiotics
-Careful assessment of patient comorbidities
-Oncologic principles for margin control.

Prognosis

Factors Affecting Prognosis:
-Stage of the cancer at diagnosis
-Histological subtype and grade
-Presence of lymph node metastasis
-Response to neoadjuvant therapy (if applicable)
-Margin status of the resection
-Patient's overall health and adherence to treatment protocols.
Outcomes:
-For oncologic indications, the prognosis is directly related to the stage of the cancer and the effectiveness of adjuvant therapies
-For reduction mammoplasty, outcomes are generally excellent, with significant improvement in symptoms and breast shape
-Aesthetic outcomes are dependent on surgical skill and patient healing, with scar appearance being a key factor.
Follow Up:
-Regular follow-up appointments are essential for oncologic patients, including clinical examinations and imaging (mammography, ultrasound) to monitor for recurrence or metastasis
-For aesthetic procedures, follow-up focuses on scar maturation, symmetry, and patient satisfaction
-Long-term surveillance is crucial for early detection of any complications or recurrence.

Key Points

Exam Focus:
-Wise pattern incision: IMF curvilinear extending superiorly
-"keyhole" or "anchor" scar
-Indications: Macromastia, ptosis with cancer, symptomatic gigantomastia
-Key oncologic principle: Adequate resection with clear margins
-Key aesthetic principle: Reshaping glandular tissue for mound formation and skin closure
-Early complications: Flap necrosis, hematoma, seroma
-Late complications: Scarring, asymmetry
-Reconstruction options: Immediate/delayed, implant/autologous.
Clinical Pearls:
-Preoperative marking is paramount for accurate dissection and symmetry
-Preserve adequate flap thickness to ensure viability
-Meticulous hemostasis prevents hematoma
-Consider contralateral symmetrization for optimal aesthetic results
-Discuss scar management openly with patients
-it’s a significant aspect of patient satisfaction
-Sentinel lymph node biopsy is standard for invasive breast cancer, even with mastectomy
-Always confirm tumor margins radiologically and pathologically.
Common Mistakes:
-Inadequate skin flap elevation leading to necrosis
-Poor hemostasis causing hematoma/seroma
-Insufficient glandular resection for oncologic safety
-Overly aggressive dissection causing NAC devascularization
-Neglecting contralateral symmetry leading to dissatisfaction
-Underestimating the importance of postoperative compression and activity restriction
-Not adequately counseling patients on scar appearance and potential complications.